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Information Journal Paper

Title

Adiponectin: Role in Physiology and Pathophysiology

Pages

  0-0

Abstract

 adiponectin, an adipokine secreted by adipocytes, is a well‑ known homeostatic factor for regulating glucose levels, lipid metabolism, and insulin sensitivity through its anti‑ infl ammatory, anti‑ fi brotic, and antioxidant effects. All these metabolic processes are mediated via two adiponectin receptors, AdipoR1 and AdipoR2. In addition, adiponectin is one of the hormones with the highest plasma concentrations. Weight loss or caloric restriction leads to increasing adiponectin levels, and this increase is associated with increased insulin sensitivity. Therefore, the adiponectin pathway can play a crucial role in the development of drugs to treat type 2 diabetes mellitus and other obesity‑ related diseases affected by insulin resistance like cancers or cardiovascular diseases. adiponectin appears to increase insulin sensitivity by improving glucose and lipid metabolisms. The objective of this review is to analyze current knowledge concerning adiponectin and, in particular, its role in physiology and pathophysiology.

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    • Cite

    APA: Copy

    Diep Nguyen, Thi Mong. (2020). Adiponectin: Role in Physiology and Pathophysiology. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, 11(-), 0-0. SID. https://sid.ir/paper/679183/en

    Vancouver: Copy

    Diep Nguyen Thi Mong. Adiponectin: Role in Physiology and Pathophysiology. INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE[Internet]. 2020;11(-):0-0. Available from: https://sid.ir/paper/679183/en

    IEEE: Copy

    Thi Mong Diep Nguyen, “Adiponectin: Role in Physiology and Pathophysiology,” INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE, vol. 11, no. -, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/679183/en

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