The Effect of 14 Days of Coenzyme Q10 Supplementation on Muscle Damage and Fatigue Indices Following a Bout Exhausting Exercise Activity in Passive Men

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Khanvari Tohid; Sardari Faramarz; Rezaei Babak

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2020 | Volume:23 | Issue:3 (145) Page(s): 386-388

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Information Journal Paper

Title

The Effect of 14 Days of Coenzyme Q10 Supplementation on Muscle Damage and Fatigue Indices Following a Bout Exhausting Exercise Activity in Passive Men

Author(s)

Khanvari Tohid | Sardari Faramarz | Rezaei Babak | Issue Writer Certificate

Keywords

Exhaustive aerobic activity

Coenzyme Q10 supplementation

Cortisol

Creatine Kinase (CK)

Inactive men

Abstract

Background and Aim Exercise aerobic is associated with increased creatine kinase and blood lactate immediately after exercise, leading to increased muscle damage and undesirable changes in many cellular markers including serum creatine kinase. In such situations, consuming nutrients and supplements such as coenzyme Q10 may prevent metabolic stress damage by increasing buffering power. However, comprehensive studies have not been performed on the effects of this nutrient on the index of muscle injury and fatigue caused by exercise. Methods & Materials For this purpose, 20 inactive volunteer men were randomly divided into two groups of 10-person Coenzyme Q10 supplement (2. 5 mg/kg body weight) and quasi-drug (2. 5 mg/kg body weight Dextrose). All subjects participated in the Bruce test exercise contract after 14 days of supplementation. Blood sampling was performed in four stages including baseline, after supplementation, immediately after exercise and two hours after exercise. Creatine kinase, lactate and Cortisol indices of both groups were measured during these four stages. Data were analyzed by means of standard deviation and repeated measures ANOVA, Bonferroni post hoc and Independent T-test using SPSS V. 17 at the significant level of 0. 05. Ethical Considerations This article has been approved by the ethics committee of Tabriz School of Medical Sciences with the ethics code IRCT 201203104663N8. Results The results showed that 14 days of Coenzyme Q10 supplementation had a significant effect on Cortisol level (P<0. 05). In addition, one session of exhausting aerobic activity increased creatinine kinase and lactate (P<0. 05). On the other hand, creatinine kinase did not differ significantly after exercise (P>0. 05). Conclusion According to the results of the present study, 14-day supplementation of Coenzyme Q10 may reduce the cellular damage induced by Exhaustive aerobic activity in Inactive men and prevent an increase in blood lactate levels.

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APA: Copy

Khanvari, Tohid, Sardari, Faramarz, & Rezaei, Babak. (2020). The Effect of 14 Days of Coenzyme Q10 Supplementation on Muscle Damage and Fatigue Indices Following a Bout Exhausting Exercise Activity in Passive Men. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 23(3 (145) ), 386-388. SID. https://sid.ir/paper/682213/en

Vancouver: Copy

Khanvari Tohid, Sardari Faramarz, Rezaei Babak. The Effect of 14 Days of Coenzyme Q10 Supplementation on Muscle Damage and Fatigue Indices Following a Bout Exhausting Exercise Activity in Passive Men. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2020;23(3 (145) ):386-388. Available from: https://sid.ir/paper/682213/en

IEEE: Copy

Tohid Khanvari, Faramarz Sardari, and Babak Rezaei, “The Effect of 14 Days of Coenzyme Q10 Supplementation on Muscle Damage and Fatigue Indices Following a Bout Exhausting Exercise Activity in Passive Men,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 23, no. 3 (145) , pp. 386–388, 2020, [Online]. Available: https://sid.ir/paper/682213/en

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