EFFECT OF TETANUS-DIPHTHERIA (TD) VACCINE ON IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTHY INDIVIDUALS WITH INSUFFICIENT IMMUNE RESPONSE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SALEHI MARYAM; HAGHIGHAT ABBAS; SALEHI HASSAN; TALEBAN ROYA; SALEHI MARZIEH; KALBASI NADER; MOAFI MOHAMMAD; SALEHI MOHAMMAD MAHDI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2015 | Volume:20 | Issue:10 Page(s): 0-0

Download Full-Text

View:

235

Download:

129

Cites:

Information Journal Paper

Title

EFFECT OF TETANUS-DIPHTHERIA (TD) VACCINE ON IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTHY INDIVIDUALS WITH INSUFFICIENT IMMUNE RESPONSE

Author(s)

Keywords

HEPATITIS B SURFACE ANTIBODY (HBSAB) TITER

HEPATITIS B VACCINE

TETANUS-DIPHTHERIA (TD) VACCINE

Abstract

Background: Hepatitis B virus (HBV) fails to produce appropriate immune responses in some healthy individuals; thus, different strategies have been adopted to promote immune responses. The current study aimed at evaluating the efficacy of HBV vaccine coadministered with tetanus-diphtheria (Td) vaccine compared with HBV vaccine in healthy individuals through measuring hepatitis B surface antibody (HBsAb) levels. Materials and Methods: This was a randomized controlled clinical trial, which was implemented in Isfahan, Isfahan Province (Iran) in 2013. One hundred and forty healthy individuals, whose HBsAb titers were less than 10 IU/L were recruited. The subjects were randomly assigned to either in intervention or control trials. The control group received 40 μg of recombinant HBV vaccines intramuscularly injected at 0, 1, and 6 months; however, the intervention group was simultaneously vaccinated by Td with the first dose of HBV vaccine. HBV antibody levels (titer) were measured before the vaccination and 6 months after the last vaccination.Results: Antibody titers of the subjects in the intervention and control groups increased from 5.07 ± 2.9 IU/L to 744.45 ± 353.07 IU/L and from 4.45 ± 3.4 IU/L to 589.94 ± 353 IU/L, respectively (both P<0.001). Also, the mean difference of antibody titer was significantly different between the two groups (P=0.011).Conclusion: Td vaccination can be applied as a feasible approach to promote efficient and persistent immunity in healthy individuals with insufficient HBsAb titers.

Cites

No record.

References

No record.

Cite

APA: Copy

SALEHI, MARYAM, HAGHIGHAT, ABBAS, SALEHI, HASSAN, TALEBAN, ROYA, SALEHI, MARZIEH, KALBASI, NADER, MOAFI, MOHAMMAD, & SALEHI, MOHAMMAD MAHDI. (2015). EFFECT OF TETANUS-DIPHTHERIA (TD) VACCINE ON IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTHY INDIVIDUALS WITH INSUFFICIENT IMMUNE RESPONSE. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(10), 0-0. SID. https://sid.ir/paper/682370/en

Vancouver: Copy

SALEHI MARYAM, HAGHIGHAT ABBAS, SALEHI HASSAN, TALEBAN ROYA, SALEHI MARZIEH, KALBASI NADER, MOAFI MOHAMMAD, SALEHI MOHAMMAD MAHDI. EFFECT OF TETANUS-DIPHTHERIA (TD) VACCINE ON IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTHY INDIVIDUALS WITH INSUFFICIENT IMMUNE RESPONSE. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(10):0-0. Available from: https://sid.ir/paper/682370/en

IEEE: Copy

MARYAM SALEHI, ABBAS HAGHIGHAT, HASSAN SALEHI, ROYA TALEBAN, MARZIEH SALEHI, NADER KALBASI, MOHAMMAD MOAFI, and MOHAMMAD MAHDI SALEHI, “EFFECT OF TETANUS-DIPHTHERIA (TD) VACCINE ON IMMUNE RESPONSE TO HEPATITIS B VACCINE IN HEALTHY INDIVIDUALS WITH INSUFFICIENT IMMUNE RESPONSE,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 10, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/682370/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops