EFFICACY OF TOPICAL ZINC SULFATE SOLUTION IN PREVENTION OF RECURRENT HERPES SIMPLEX INFECTIONS

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PEZESHK POUR F.; LAYEGH POURAN

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Journal: Internal Medicine Today Year:2004 | Volume:9 | Issue:2 Page(s): 16-22

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Information Journal Paper

Title

EFFICACY OF TOPICAL ZINC SULFATE SOLUTION IN PREVENTION OF RECURRENT HERPES SIMPLEX INFECTIONS

Author(s)

PEZESHK POUR F. | LAYEGH POURAN | Issue Writer Certificate

Keywords

RECURRENT INFECTIONQ4

HERPES SIMPLEXQ4

ZINC SULFATEQ4

Abstract

Background and Aim: More than 85% of world population is infected with HERPES SIMPLEX virus. From unique characteristics of this virus is disability of eradication of it after infection. Until now multiple methods have been examined for treatment and prevention of recurrent episodes and its complications, but finding of more effective, low cost and available way with few adverse reaction is considered by researchers. Materials and Methods: In these prospective clinical trial 40 patients with recurrent HERPES SIMPLEX infection (more than three times episodes per year) treated with 0.05% ZINC SULFATE solution once daily for 5-10 minutes during episodes and then once per week until at least one month after recovery. Then patients followed up for six months later and in each follow up visit evaluated for characteristics such as frequency, duration of episodes and change in severity of lesions. Results: Evaluation of therapeutic response of the patients in three consecutive follow up visit in first, 3thand 6thmonth after ending of treatment showed significant effectiveness of this drug on reduction of frequency ( p=0.0002) , reduction of severity ( p=0.02) but no significant change on duration of recurrent HERPES SIMPLEX episodes was showed. Conclusion: ZINC SULFATE solution is an effective, available and low cost treatment but with delayed effects in prevention of recurrent HERPES SIMPLEX episodes.

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APA: Copy

PEZESHK POUR, F., & LAYEGH, POURAN. (2004). EFFICACY OF TOPICAL ZINC SULFATE SOLUTION IN PREVENTION OF RECURRENT HERPES SIMPLEX INFECTIONS. OFOGH-E-DANESH, 9(2), 16-22. SID. https://sid.ir/paper/68375/en

Vancouver: Copy

PEZESHK POUR F., LAYEGH POURAN. EFFICACY OF TOPICAL ZINC SULFATE SOLUTION IN PREVENTION OF RECURRENT HERPES SIMPLEX INFECTIONS. OFOGH-E-DANESH[Internet]. 2004;9(2):16-22. Available from: https://sid.ir/paper/68375/en

IEEE: Copy

F. PEZESHK POUR, and POURAN LAYEGH, “EFFICACY OF TOPICAL ZINC SULFATE SOLUTION IN PREVENTION OF RECURRENT HERPES SIMPLEX INFECTIONS,” OFOGH-E-DANESH, vol. 9, no. 2, pp. 16–22, 2004, [Online]. Available: https://sid.ir/paper/68375/en

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