EFFICACY OF COMPOUND THERAPY BY GINSENG AND CIPROFLOXACIN ON BACTERIAL PROSTATITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MIRI MARYAM; SHOKRI SAEED; DARABI SHAHRAM; ALIPOUR HEIDARI MAHMOOD; GHALYANCHI AKHGAR; KARIMFAR MOHAMMAD HASSAN; SHIRAZI REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Cell Journal (Yakhteh) Year:2016 | Volume:18 | Issue:1 (69) Page(s): 103-111

Download Full-Text

View:

432

Download:

278

Cites:

Information Journal Paper

Title

EFFICACY OF COMPOUND THERAPY BY GINSENG AND CIPROFLOXACIN ON BACTERIAL PROSTATITIS

Author(s)

Keywords

GINSENG

PROSTATE

INFECTION

CIPROFLOXACIN

Abstract

Objective: Genitourinary tract INFECTIONs play a significant role in male infertility. INFECTIONs of reproductive sex glands, such as the PROSTATE, impair function and indirectly affect male fertility. The general aim of this study is to investigate the protective effect of Korean red GINSENG (KRG) on prostatitis in male rats treated with CIPROFLOXACIN (CIPX).Materials and Methods: In this experimental study, we randomly divided 72 two male Wistar rats into 9 groups. The groups were treated as follows for 10 days: i. Control (no medication), ii. Sham [(normal saline injection into the vas deferens and oral administration of phosphate-buffered saline (PBS)], iii. GINSENG, iv. CPIX, v. CIPX+GINSENG, vi. Uropathogenic Escherichia coli (E. coli) (UPEC), vii. UPEC+GINSENG, viii. UPEC+CIPX, and ix. UPEC+GINSENG+CIPX. The rats were killed 14 days after the last injection and the PROSTATE glands were removed. After sample preparation, routine histology was performed using hematoxylin and eosin staining. The terminal deoxynucleotidyl transferase mediated dUTP-biotin nick end labeling (TUNEL) method was used to determine the presence of apoptotic cells.Results: The severity score for acinar changes and inflammatory cell infiltration in the UPEC+CIPX group did not significantly different from the UPEC group. However this score significantly decreased in the UPEC+CIPX+GINSENG group compared to the UPEC group. Apoptotic index of all GINSENG treated groups significantly decreased compared to the UPEC and CPIX groups.Conclusion: These results suggested that GINSENG might be an effective adjunct in CIPX treatment of prostatitis. The combined use GINSENG and CIPX was more effective than GINSENG or CIPX alone.

Cites

No record.

References