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Title

APPROACH TO PATIENTS WITH SEVERE ASTHMA: A CONSENSUS STATEMENT FROM THE RESPIRATORY CARE EXPERTS’ INPUT FORUM (RC-EIF), IRAN

Pages

  73-94

Abstract

 Challenges in the assessment, diagnosis and management of severe, difficult-to-control asthma are increasingly regarded as clinical needs yet unmet. The assessments required to determine asthma severity, COMORBIDITIES and confounding factors, disease phenotypes and optimal TREATMENT are among the controversial issues in the field.The respiratory care experts’ input forum (RC-EIF), comprised of an IRANian panel of experts, reviewed the DEFINITION, appraised the available guidelines and provided a consensus for evaluation and TREATMENT of SEVERE ASTHMA in adults.A systematic literature review followed by discussions during and after the forum, yielded the present consensus. The expert panel used the appraisal of guidelines for research and evaluation-II (AGREE-II) protocol to define an initial locally-adapted strategy for the management of SEVERE ASTHMA.SEVERE ASTHMA is considered a heterogeneous condition with various phenotypes. Issues such as assessment of difficult-tocontrol asthma, PHENOTYPING, the use of blood and sputum eosinophil count, exhaled nitric oxide to guide therapy, the position of anti-IgE antibody, methotrexate, macrolide antibiotics, antifungal agents and bronchial thermoplasty as well as the use of established, recently-developed and evolving TREATMENT approaches were discussed and unanimously agreed upon in the panel.A systematic approach is required to ensure proper diagnosis, evaluate compliance, and to identify COMORBIDITIES and triggering factors in SEVERE ASTHMA. PHENOTYPING helps select optimized TREATMENT. The TREATMENT approach laid down by the Global Initiative for Asthma (GINA) needs to be followed, while the benefit of using biological therapies should be weighed against the cost and safety concerns.

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    APA: Copy

    ANSARIN, KHALIL, ATTARAN, DAVOOD, JAMAATI, HAMID REZA, MASJEDI, MOHAMMAD REZA, ABTAHI, HAMIDREZA, ALAVI, ALI, ALIYALI, MASOUD, HASHEM ASNAASHARI, AMIR MOHAMAD, FARID HOSSEINI, REZA, GHAYUMI, SEIYED MOHAMMAD ALI, GHOBADI, HASSAN, GHOTB, ATABAK, HALVANI, ABOLHASAN, NEMATI, ABBAS, RAHIMIRAD, MOHAMMAD HOSSEIN, Rahimian, Masoud, SAMI, RAMIN, SOHRABPOUR, HAMID, TAVANA, SASAN, TORABI NAMI, MOHAMMAD, & VAHEDI, PARVIZ. (2015). APPROACH TO PATIENTS WITH SEVERE ASTHMA: A CONSENSUS STATEMENT FROM THE RESPIRATORY CARE EXPERTS’ INPUT FORUM (RC-EIF), IRAN. TANAFFOS, 14(2), 73-94. SID. https://sid.ir/paper/684330/en

    Vancouver: Copy

    ANSARIN KHALIL, ATTARAN DAVOOD, JAMAATI HAMID REZA, MASJEDI MOHAMMAD REZA, ABTAHI HAMIDREZA, ALAVI ALI, ALIYALI MASOUD, HASHEM ASNAASHARI AMIR MOHAMAD, FARID HOSSEINI REZA, GHAYUMI SEIYED MOHAMMAD ALI, GHOBADI HASSAN, GHOTB ATABAK, HALVANI ABOLHASAN, NEMATI ABBAS, RAHIMIRAD MOHAMMAD HOSSEIN, Rahimian Masoud, SAMI RAMIN, SOHRABPOUR HAMID, TAVANA SASAN, TORABI NAMI MOHAMMAD, VAHEDI PARVIZ. APPROACH TO PATIENTS WITH SEVERE ASTHMA: A CONSENSUS STATEMENT FROM THE RESPIRATORY CARE EXPERTS’ INPUT FORUM (RC-EIF), IRAN. TANAFFOS[Internet]. 2015;14(2):73-94. Available from: https://sid.ir/paper/684330/en

    IEEE: Copy

    KHALIL ANSARIN, DAVOOD ATTARAN, HAMID REZA JAMAATI, MOHAMMAD REZA MASJEDI, HAMIDREZA ABTAHI, ALI ALAVI, MASOUD ALIYALI, AMIR MOHAMAD HASHEM ASNAASHARI, REZA FARID HOSSEINI, SEIYED MOHAMMAD ALI GHAYUMI, HASSAN GHOBADI, ATABAK GHOTB, ABOLHASAN HALVANI, ABBAS NEMATI, MOHAMMAD HOSSEIN RAHIMIRAD, Masoud Rahimian, RAMIN SAMI, HAMID SOHRABPOUR, SASAN TAVANA, MOHAMMAD TORABI NAMI, and PARVIZ VAHEDI, “APPROACH TO PATIENTS WITH SEVERE ASTHMA: A CONSENSUS STATEMENT FROM THE RESPIRATORY CARE EXPERTS’ INPUT FORUM (RC-EIF), IRAN,” TANAFFOS, vol. 14, no. 2, pp. 73–94, 2015, [Online]. Available: https://sid.ir/paper/684330/en

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