CHANGES IN GROWTH FACTORS AND ESTROGENS IN COURSE OF BREAST CANCER: ROLE OF THE INDIVIDUAL AND COMBINED OF WATER-BASED EXERCISE AND GINGER SUPPLEMENTATION

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GHORBANI SHORKAII Z.; DABIDI ROSHAN V.

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Journal: Internal Medicine Today Year:2014 | Volume:19 | Issue:4 Page(s): 198-205

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Information Journal Paper

Title

CHANGES IN GROWTH FACTORS AND ESTROGENS IN COURSE OF BREAST CANCER: ROLE OF THE INDIVIDUAL AND COMBINED OF WATER-BASED EXERCISE AND GINGER SUPPLEMENTATION

Author(s)

GHORBANI SHORKAII Z. | DABIDI ROSHAN V. | Issue Writer Certificate

Keywords

ESTROGENSQ2

EXERCISEQ1

GINGERQ2

BREAST NEOPLASMSQ2

RECEPTORS/GROWTH FACTORQ2

Abstract

Aims: Growth factors are associated with a change in body composition and chronic diseases such as; cancer. The aim of this study was to determine the individual and concomitant effect of water-based EXERCISE and oral Zingiber officinale supplement on Changes in growth factors and estrogen in overweight women with breast cancer.Methods: In a semi-experimental study, Forty obese women diagnosed with breast cancer (76±9 kg, fat mass 41.8±4 percent) participated. Subjects were randomly assigned into groups; placebo, water-based EXERCISE, Zingiber and water-based EXERCISE+Zingiber groups. Subjects in the Zingiber group and combined group orally received 4 capsules contained 750 mg of zingiber flour for 6 weeks. The water-based EXERCISE program were collected at a progressive intensity and time, ranged from 50 to 75 percent of heart rate reserve, for 6 weeks. Fasting blood sampling was collected at the pretest and post-test.Results: Although, the Zingiber and or the water-base EXERCISE resulted in a reduction in IGF-1 and estrogen levels and a increase in IGFBP-3 levels, changes in the index following the combined intervention (exercise in water+Ginger supplements) were more pronounced compared with pre-test and the control group. However, there was the significant difference only in IGFBP-3 levels between water-base EXERCISE and Zingiber supplementation groups (p=0.046).Conclusion: Our findings indicate a protective effect of the nondrug strategies such as EXERCISE in water and anti-inflammatory herbal factors in the pathogenesis of growth and metabolic responses in overweight women diagnosed with breast cancer.

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APA: Copy

GHORBANI SHORKAII, Z., & DABIDI ROSHAN, V.. (2014). CHANGES IN GROWTH FACTORS AND ESTROGENS IN COURSE OF BREAST CANCER: ROLE OF THE INDIVIDUAL AND COMBINED OF WATER-BASED EXERCISE AND GINGER SUPPLEMENTATION. OFOGH-E-DANESH, 19(4), 198-205. SID. https://sid.ir/paper/68532/en

Vancouver: Copy

GHORBANI SHORKAII Z., DABIDI ROSHAN V.. CHANGES IN GROWTH FACTORS AND ESTROGENS IN COURSE OF BREAST CANCER: ROLE OF THE INDIVIDUAL AND COMBINED OF WATER-BASED EXERCISE AND GINGER SUPPLEMENTATION. OFOGH-E-DANESH[Internet]. 2014;19(4):198-205. Available from: https://sid.ir/paper/68532/en

IEEE: Copy

Z. GHORBANI SHORKAII, and V. DABIDI ROSHAN, “CHANGES IN GROWTH FACTORS AND ESTROGENS IN COURSE OF BREAST CANCER: ROLE OF THE INDIVIDUAL AND COMBINED OF WATER-BASED EXERCISE AND GINGER SUPPLEMENTATION,” OFOGH-E-DANESH, vol. 19, no. 4, pp. 198–205, 2014, [Online]. Available: https://sid.ir/paper/68532/en

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