THE COMPARISON OF ATRACURIUM AND LIDOCAINE FOR DECREASING SUCCINYLCHOLINE INDUCED FASCICULATION, MYALGIA AND SERUM POTASSIUM CHANGE IN PATIENTS DURING INDUCTION OF ANESTHESIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOKARAM M.; KHOUSHFETRAT MASOUM; SAHEBAN MALEKI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Internal Medicine Today Year:2009 | Volume:14 | Issue:4 Page(s): 39-47

Download Full-Text

Persian Verion

View:

929

Download:

Cites:

Information Journal Paper

Title

THE COMPARISON OF ATRACURIUM AND LIDOCAINE FOR DECREASING SUCCINYLCHOLINE INDUCED FASCICULATION, MYALGIA AND SERUM POTASSIUM CHANGE IN PATIENTS DURING INDUCTION OF ANESTHESIA

Author(s)

MOKARAM M. | KHOUSHFETRAT MASOUM | SAHEBAN MALEKI M. | Issue Writer Certificate

Keywords

SUCCINYLCHOLINEQ3

FASCICULATIONQ3

MYALGIAQ2

HYPERKALEMIAQ2

Abstract

Background and Aim: In the patients at risk of aspiration, it is necessary to induce general anesthesia and intubate their trachea as rapid sequence. SUCCINYLCHOLINE is the only neuromascular blocker with short onset and ultrashort acting effect, therefore choice of drug is in rapid sequence induction of anesthesia. This drug has many advantages, including low cost, short onset, short duration of action, and profound muscle relaxation with no need to reversal of muscle relaxation. The most important side effects of this drug are FASCICULATION, postoperative MYALGIA and rise in serum potassium. We compared Lidocaine with Atracurium in preventing these side effects.Materials and Methods: The patients aged 20-50 years, in class I or II physical status (ASA), were randomly assigned either to group A or group B. Those in group A were given Atracurium (0.05 mg/kg), 3 minutes before SUCCINYLCHOLINE. Those in group B received Lidocaine (1.5 mg/kg), 30 seconds before SUCCINYLCHOLINE at induction of anesthesia. All patients in both groups received Sodium Thiopental (4 mg/kg) and SUCCINYLCHOLINE 1.5 mg/kg at induction of anesthesia. We evaluated and recorded FASCICULATION and MYALGIA in two days after operation. We also measured serum potassium before induction and 5 minutes after SUCCINYLCHOLINE injection. In order to control of post-operative pain, we used intravenous Morphine or Acetaminophen as either oral or suppository. Results: 160 patients were studied. The occurrence and severity of FASCICULATION were the same in two groups (p>0.05). There were less MYALGIA in group B in comparison with group A, one and two days after operation (p<0.05). There were no significant changes in serum potassium in two groups. Conclusion: Lidocaine is as effective as Atracurium in decreasing the occurrence and severity of FASCICULATION, following SUCCINYLCHOLINE injection at induction of anesthesia. Lidocaine is more effective than Atracurium in decreasing the occurrence and severity of MYALGIA.

Cites

No record.

References

No record.

Cite

APA: Copy

MOKARAM, M., KHOUSHFETRAT, MASOUM, & SAHEBAN MALEKI, M.. (2009). THE COMPARISON OF ATRACURIUM AND LIDOCAINE FOR DECREASING SUCCINYLCHOLINE INDUCED FASCICULATION, MYALGIA AND SERUM POTASSIUM CHANGE IN PATIENTS DURING INDUCTION OF ANESTHESIA. OFOGH-E-DANESH, 14(4), 39-47. SID. https://sid.ir/paper/68549/en

Vancouver: Copy

MOKARAM M., KHOUSHFETRAT MASOUM, SAHEBAN MALEKI M.. THE COMPARISON OF ATRACURIUM AND LIDOCAINE FOR DECREASING SUCCINYLCHOLINE INDUCED FASCICULATION, MYALGIA AND SERUM POTASSIUM CHANGE IN PATIENTS DURING INDUCTION OF ANESTHESIA. OFOGH-E-DANESH[Internet]. 2009;14(4):39-47. Available from: https://sid.ir/paper/68549/en

IEEE: Copy

M. MOKARAM, MASOUM KHOUSHFETRAT, and M. SAHEBAN MALEKI, “THE COMPARISON OF ATRACURIUM AND LIDOCAINE FOR DECREASING SUCCINYLCHOLINE INDUCED FASCICULATION, MYALGIA AND SERUM POTASSIUM CHANGE IN PATIENTS DURING INDUCTION OF ANESTHESIA,” OFOGH-E-DANESH, vol. 14, no. 4, pp. 39–47, 2009, [Online]. Available: https://sid.ir/paper/68549/en

Related Journal Papers