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Information Journal Paper

Title

Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran

Pages

  0-0

Abstract

 Background: Human Parvovirus B19 is a single-stranded DNA and non-enveloped virus which belongs to the Parvoviridae family. The virus spreads through respiratory secretions and perinatal blood. B19 may cause serious complications in patients with cellular immunodeficiency that have no detectable antibodies to B19, such as aplastic crises in solid organs. Objectives: The present study aimed to investigate the prevalence of Parvovirus B19 and to evaluate the presence of B19 DNA among Blood Donors in Golestan Province. Methods: Sera of 400 Blood Donors in Golestan Province who were negative for HIV, HbsAg, and HCV were tested for both IgG and IgManti-B19 virus antibodies using the ELISA method, followingwhichall sera were tested for the presence of B19DNAby semi-nested PCR. Results: 242 (out of 400) subjects (60. 5%; 95% CI) were positive for anti-B19 IgG, and158 were negative for IgG antibody (39. 5%; 95% CI). Moreover, all asymptomatic Blood Donors were negative for anti-B19 IgM. No viral genome was found in serum samples of donors. Conclusions: Since no viral genome was found in the donors’ serum samples and the relatively high prevalence of anti HPV-B19 IgG in Blood Donors, it can be concluded that the possibility of B19 transmission through blood transfusion is low. However, special caution should be taken when transfusing blood to the high-risk groups such as pregnant women, immune-deficient patients, and those with hematological problems, particularly regarding IgG anti-HPV-B19 antibodies (HPV-B19-safe).

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    APA: Copy

    Karimnia, Ameneh, Elikaei, Ameneh, & SHARIFI, ZOHREH. (2020). Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran. ARCHIVES OF CLINICAL INFECTIOUS DISEASES, 15(4), 0-0. SID. https://sid.ir/paper/686431/en

    Vancouver: Copy

    Karimnia Ameneh, Elikaei Ameneh, SHARIFI ZOHREH. Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran. ARCHIVES OF CLINICAL INFECTIOUS DISEASES[Internet]. 2020;15(4):0-0. Available from: https://sid.ir/paper/686431/en

    IEEE: Copy

    Ameneh Karimnia, Ameneh Elikaei, and ZOHREH SHARIFI, “Human Parvovirus B19 Infection Among Blood Donors in North-East of Iran,” ARCHIVES OF CLINICAL INFECTIOUS DISEASES, vol. 15, no. 4, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/686431/en

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