Does curcumin have an effect on sleep duration in metabolic syndrome patients?

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Saberi Karimian Maryam; Ghazizadeh Hamideh; MOHAMMADZADEH ELHAM; FERNS GORDON A.; GHAYOUR MOBARHAN MAJID; Sahebkar Amirhosein

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Journal: Avicenna Journal of Phytomedicine Year:2021 | Volume:11 | Issue:2 Page(s): 190-198

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Title

Does curcumin have an effect on sleep duration in metabolic syndrome patients?

Author(s)

Keywords

Curcumin

Sleep duration

Metabolic syndrome

Abstract

Objective: Sleep-duration is related to obesity. Curcumin can affect behavioral changes that arise from sleep deprivation in animal models. In this study, we assessed the effects of Curcumin on sleep-duration in metabolic-syndrome (MetS) patients. Materials and Methods: This study was a double-blind clinical trial in 120 adults with MetS. All participants received crude Curcuminoids in a simple formulation (n=40), phospholipidated Curcuminoids (n=40) or placebo (n=40) 1 g/day during 6 weeks. Demographic data, anthropometric indices and serum biochemical factors were documented for all volunteers at baseline and after the intervention. A standard questionnaire was used for evaluating physical-activity-level (PAL) and patients’ sleep-duration, including night time sleep and daily napping. Based on the time of sleep, sleeping hours were classified into: night time sleep; daily naps and total sleeping hours in 24 hours. Results: A total of 120 participants aged 38. 72± 10. 05 years old were enrolled into the study. We did not find significant differences in biochemical factors, sleep-duration or PAL at baseline among the 3 groups (p>0· 05). Moreover, Curcumin did not exert any significant effect on sleep-duration before, or after, adjustment for confounding factors in the overweight and obese individuals, or in total population (p>0. 05). Conclusion: The results showed that Curcumin does not have an effect on sleep-duration in subject with MetS.

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APA: Copy

Saberi Karimian, Maryam, Ghazizadeh, Hamideh, MOHAMMADZADEH, ELHAM, FERNS, GORDON A., GHAYOUR MOBARHAN, MAJID, & Sahebkar, Amirhosein. (2021). Does curcumin have an effect on sleep duration in metabolic syndrome patients?. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), 11(2), 190-198. SID. https://sid.ir/paper/687057/en

Vancouver: Copy

Saberi Karimian Maryam, Ghazizadeh Hamideh, MOHAMMADZADEH ELHAM, FERNS GORDON A., GHAYOUR MOBARHAN MAJID, Sahebkar Amirhosein. Does curcumin have an effect on sleep duration in metabolic syndrome patients?. AVICENNA JOURNAL OF PHYTOMEDICINE (AJP)[Internet]. 2021;11(2):190-198. Available from: https://sid.ir/paper/687057/en

IEEE: Copy

Maryam Saberi Karimian, Hamideh Ghazizadeh, ELHAM MOHAMMADZADEH, GORDON A. FERNS, MAJID GHAYOUR MOBARHAN, and Amirhosein Sahebkar, “Does curcumin have an effect on sleep duration in metabolic syndrome patients?,” AVICENNA JOURNAL OF PHYTOMEDICINE (AJP), vol. 11, no. 2, pp. 190–198, 2021, [Online]. Available: https://sid.ir/paper/687057/en

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