EFFICACY OF BOLUS INSULIN CALCULATION BY A MOBILE-BASED BOLUS ADVISOR: AN OPEN LABEL CLINICAL TRIAL

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SIAVASH MANSOOR; TAHERIAN MOHSEN; ATAEI KHORASGANI MASOUD

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Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2015 | Volume:20 | Issue:11 Page(s): 0-0

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Title

EFFICACY OF BOLUS INSULIN CALCULATION BY A MOBILE-BASED BOLUS ADVISOR: AN OPEN LABEL CLINICAL TRIAL

Author(s)

SIAVASH MANSOOR | TAHERIAN MOHSEN | ATAEI KHORASGANI MASOUD | Issue Writer Certificate

Keywords

BOLUS CALCULATOR; CARBOHYDRATE COUNTING; INTENSIVE GLYCEMIC CONTROL; INSULIN THERAPY

Abstract

Background: We investigated the efficacy of a mobile-based bolus advisor app in comparison with the usual multiple daily injections(MDIs) in diabetic patients. Materials and Methods: In a nonrandomized, controlled clinical trial, 62 diabetic patients wereselected to receive a 12-week intensive glycemic control by either a mobile-based bolus advisor (app) or MDI in the usual manner.We compared mean blood glucose (BG) and HbA1c before and just after the treatment program. The data were analyzed usingpaired sample t-test and analysis of variance (ANOVA).Results: Fifty-six patients (30 cases and 26 controls) completed the study.The mean [standard deviation (SD)] of BG was 220.57 (43.7) and 231.5 (55) in the app group and control group, respectively. MeanBG decreased 38 mg/dL in the app and 16 mg/dL in the control group (P=0.001 and 0.049 respectively). Changes of mean BG weredifferent between the two groups significantly (P=0.039). HbA1c decreased from 8.4% to 7.6% in the case and from 8.4% to 8% inthe control group (P=0.001 and 0.06, respectively). Changes of HbA1c were not different between the two groups (P=0.141). Themean episodes of hypoglycemia were not different between the groups significantly (P=0.108).Conclusion: In conclusion, this studyrevealed that mobile-based bolus advisors can reduce mean BG better in patients who are planned to have a tight glycemic controlas a feasible and available method and may improve HbA1c in the long term.

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APA: Copy

SIAVASH, MANSOOR, TAHERIAN, MOHSEN, & ATAEI KHORASGANI, MASOUD. (2015). EFFICACY OF BOLUS INSULIN CALCULATION BY A MOBILE-BASED BOLUS ADVISOR: AN OPEN LABEL CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 20(11), 0-0. SID. https://sid.ir/paper/688539/en

Vancouver: Copy

SIAVASH MANSOOR, TAHERIAN MOHSEN, ATAEI KHORASGANI MASOUD. EFFICACY OF BOLUS INSULIN CALCULATION BY A MOBILE-BASED BOLUS ADVISOR: AN OPEN LABEL CLINICAL TRIAL. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2015;20(11):0-0. Available from: https://sid.ir/paper/688539/en

IEEE: Copy

MANSOOR SIAVASH, MOHSEN TAHERIAN, and MASOUD ATAEI KHORASGANI, “EFFICACY OF BOLUS INSULIN CALCULATION BY A MOBILE-BASED BOLUS ADVISOR: AN OPEN LABEL CLINICAL TRIAL,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 20, no. 11, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/688539/en

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