Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

287
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

208
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

SIGNALING MOLECULES GOVERNING PLURIPOTENCY AND EARLY LINEAGE COMMITMENTS IN HUMAN PLURIPOTENT STEM CELLS (REVIEW ARTICLE)

Pages

  194-203

Abstract

 Signaling in pluripotent STEM CELLs is a complex and dynamic process involving multiple mediators, finely tuned to balancing pluripotency and DIFFERENTIATION states. Characterizing and modifying the necessary signaling pathways to attain desired cell types is required for stem-cell applications in various fields of regenerative medicine. These signals may help enhance the DIFFERENTIATION potential of pluripotent cells towards each of the embryonic lineages and enable us to achieve pure in vitro cultures of various cell types. This review provides a timely synthesis of recent advances into how maintenance of pluripotency in hPSCs is regulated by extrinsic cues, such as the fibroblast growth factor (FGF) and ACTIVIN signaling pathways, their interplay with other signaling pathways, namely, wingless-type MMTV integration site family (WNT) and mammalian target of rapamycin (mTOR), and the pathways governing the determination of multiple lineages.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    FATHI, ALI, EISA BEYGI, SHAHRAM, & BAHARVAND, HOSSEIN. (2017). SIGNALING MOLECULES GOVERNING PLURIPOTENCY AND EARLY LINEAGE COMMITMENTS IN HUMAN PLURIPOTENT STEM CELLS (REVIEW ARTICLE). CELL JOURNAL (YAKHTEH), 19(2), 194-203. SID. https://sid.ir/paper/688566/en

    Vancouver: Copy

    FATHI ALI, EISA BEYGI SHAHRAM, BAHARVAND HOSSEIN. SIGNALING MOLECULES GOVERNING PLURIPOTENCY AND EARLY LINEAGE COMMITMENTS IN HUMAN PLURIPOTENT STEM CELLS (REVIEW ARTICLE). CELL JOURNAL (YAKHTEH)[Internet]. 2017;19(2):194-203. Available from: https://sid.ir/paper/688566/en

    IEEE: Copy

    ALI FATHI, SHAHRAM EISA BEYGI, and HOSSEIN BAHARVAND, “SIGNALING MOLECULES GOVERNING PLURIPOTENCY AND EARLY LINEAGE COMMITMENTS IN HUMAN PLURIPOTENT STEM CELLS (REVIEW ARTICLE),” CELL JOURNAL (YAKHTEH), vol. 19, no. 2, pp. 194–203, 2017, [Online]. Available: https://sid.ir/paper/688566/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top