RELATIONSHIP BETWEEN METABOLIC SYNDROME AND ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE

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MIRI REZA; SAJJADIEH AMIR; PARSAMAHJOOB MOHAMMAD; HAJIBARATALI BAHAREH; SHEKARCHIZADEH MASOOD; KOLAHI ALI ASGHAR; SADEGHI MEHRAN; AHMADI ZAHRA; FARMANARA HAMEDREZA; SHEKARCHIZADEH ESFAHANI MANSOUREH

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Journal: ARYA Atherosclerosis Year:2016 | Volume:12 | Issue:5 Page(s): 220-225

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Title

RELATIONSHIP BETWEEN METABOLIC SYNDROME AND ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE

Author(s)

Keywords

METABOLIC SYNDROME

ANGIOGRAPHY

SEVERITY

CORONARY ARTERY DISEASE

Abstract

BACKGROUND: There are a few literature data on the correlation between METABOLIC SYNDROME (MetS) and coronary disease among Iranian population. This study aimed to find relationship between MetS and SEVERITY of CORONARY ARTERY DISEASE (CAD) in presence of diabetes.METHODS: Total of 192 patients were consecutively enrolled in the study who were admitted to coronary care unit because of acute coronary syndrome (ACS) and then underwent coronary ANGIOGRAPHY. MetS was defined by Iranian criteria. A coronary atherosclerosis score was used to quantify the extent of atherosclerotic involvement. The relationship between MetS and angiographic CORONARY ARTERY DISEASE (CAD) SEVERITY or clinical presentation was compared between them after adjusting for diabetes.RESULTS: Individuals with MetS (n=125) had a higher prevalence of ST-elevation myocardial infarction (71% vs 30%, P<0.001), multi-vessel disease (50% vs.34%, P=0.003), decreased ejection fraction (P=0.001) and more severe angiographic stenosis based on both modified Gensini (P=0.081) and syntax (P=0.008) scores, compared to those without MetS. Syntax score showed statistically significant difference between two groups before (P=0.021) and after adjustment for diabetes (P=0.005).CONCLUSION: MetS was related to the SEVERITY of CAD both clinically and by angiographic scores but diabetes was a challenging factor and may independently increase the SEVERITY of CAD.

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APA: Copy

MIRI, REZA, SAJJADIEH, AMIR, PARSAMAHJOOB, MOHAMMAD, HAJIBARATALI, BAHAREH, SHEKARCHIZADEH, MASOOD, KOLAHI, ALI ASGHAR, SADEGHI, MEHRAN, AHMADI, ZAHRA, FARMANARA, HAMEDREZA, & SHEKARCHIZADEH ESFAHANI, MANSOUREH. (2016). RELATIONSHIP BETWEEN METABOLIC SYNDROME AND ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE. ARYA ATHEROSCLEROSIS, 12(5), 220-225. SID. https://sid.ir/paper/688679/en

Vancouver: Copy

MIRI REZA, SAJJADIEH AMIR, PARSAMAHJOOB MOHAMMAD, HAJIBARATALI BAHAREH, SHEKARCHIZADEH MASOOD, KOLAHI ALI ASGHAR, SADEGHI MEHRAN, AHMADI ZAHRA, FARMANARA HAMEDREZA, SHEKARCHIZADEH ESFAHANI MANSOUREH. RELATIONSHIP BETWEEN METABOLIC SYNDROME AND ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE. ARYA ATHEROSCLEROSIS[Internet]. 2016;12(5):220-225. Available from: https://sid.ir/paper/688679/en

IEEE: Copy

REZA MIRI, AMIR SAJJADIEH, MOHAMMAD PARSAMAHJOOB, BAHAREH HAJIBARATALI, MASOOD SHEKARCHIZADEH, ALI ASGHAR KOLAHI, MEHRAN SADEGHI, ZAHRA AHMADI, HAMEDREZA FARMANARA, and MANSOUREH SHEKARCHIZADEH ESFAHANI, “RELATIONSHIP BETWEEN METABOLIC SYNDROME AND ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE,” ARYA ATHEROSCLEROSIS, vol. 12, no. 5, pp. 220–225, 2016, [Online]. Available: https://sid.ir/paper/688679/en

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