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Information Journal Paper

Title

Adverse Drug Reactions of Antiepileptic Drugs in the Neurology Department of a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India

Pages

  0-0

Abstract

 Background: Epilepsy is a disorder that affects 1% of the global population. It is the second most common serious neurologic disorder after stroke, affecting humans. Since Antiepileptic Drugs have a narrow therapeutic index and their adverse effects can affect any organ, their widespread use has significant safety implications. Objectives: The study assessed Adverse Drug Reactions (ADRs) using Antiepileptic Drugs in the Department of Neurology at a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India. Methods: This prospective observational study was conducted in the Department of Neurology of a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India, for eight months. It was a spontaneous reporting of ADRs by practicing physicians in the outpatient and inpatient settings that were included in the study. Results: Of the 3, 300 patients who were on the anti-epileptic drug (AED), 92 (3. 07%) had AED-related ADRs. A total of 18 cases were reported in the inpatient department and 74 cases in the outpatient setting. The most common ADRs were loss of appetite (34. 78%), skin rashes (17. 39%), and gum hypertrophy (9. 78%). Of 80 ADRs, 42. 5% were related to valproate, followed by phenytoin, carbamazepine, and levetiracetam. The suspected drug was changed in 22 patients with ADRs. Conclusions: For the early diagnosis and avoidance of ADRs, the frequent follow-up of patients on AEDs is needed to improve patient compliance with drug therapy and provide better drug therapy for avoiding associated morbidity and mortality.

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    APA: Copy

    Maqbool, Mudasir, Dugassa, Dinka, & Fekadu, Ginenus. (2021). Adverse Drug Reactions of Antiepileptic Drugs in the Neurology Department of a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India. ARCHIVES OF NEUROSCIENCE, 8(2), 0-0. SID. https://sid.ir/paper/691366/en

    Vancouver: Copy

    Maqbool Mudasir, Dugassa Dinka, Fekadu Ginenus. Adverse Drug Reactions of Antiepileptic Drugs in the Neurology Department of a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India. ARCHIVES OF NEUROSCIENCE[Internet]. 2021;8(2):0-0. Available from: https://sid.ir/paper/691366/en

    IEEE: Copy

    Mudasir Maqbool, Dinka Dugassa, and Ginenus Fekadu, “Adverse Drug Reactions of Antiepileptic Drugs in the Neurology Department of a Tertiary Care Hospital, Srinagar, Jammu & Kashmir, India,” ARCHIVES OF NEUROSCIENCE, vol. 8, no. 2, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/691366/en

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