مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

SARS-COV-2: History, Genetics, and Treatment

Pages

  666-669

Abstract

 Background and Aim Coronaviruses are a large family of viruses that cause disease in humans and animals. Coronavirus Disease 2019 (COVID-19) is an acute respiratory infectious disease caused by a new coronavirus. The World Health Organization has declared this infectious disease as a global pandemic. Objective: This study aims to review the latest research advances in Genetics, pathogenicity, and clinical features of COVID-19, as well as current therapies to combat this disease. Methods & Materials This is a systematic review study on articles published from 2010 to 2020 by searching in reputable databases such as PubMed, Scopus, Google Scholar, Web of Science, and ScienceDirect. Ethical Considerations Ethical principles have been observed in accordance with the guidelines of the National Ethics Committee and the COPE regulations. Results Examining the genome and genetic studies of the virus, it can be said that there are many similarities between different coronavirus types, but there are differences in their genomic and phenotypic structures that can affect their pathogenesis. Re-use of existing therapeutic drugs, previously designed for other infections and viral pathologies is currently the only practical approach to fight COVID-19. The tests for SARS-CoV-2 genome-specific vaccines and the therapeutic antibodies are currently being tested, but they require a long-term process and complete safety testing. Conclusion Rapid diagnosis of SARS-CoV-2 infection is the basis of disease control. There is currently no specific antiviral drug approved for SARS-CoV-2 infection. Therefore, preventive measures are necessary to stop and control the spread of COVID-19, according to genetic studies and the obtaining knowledge of the molecular mechanism of this virus.

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    • Cite

    APA: Copy

    Agharezaee, Niloofar, & FOROUZESH, FLORA. (2021). SARS-COV-2: History, Genetics, and Treatment. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 23(5 (147) ), 666-669. SID. https://sid.ir/paper/691890/en

    Vancouver: Copy

    Agharezaee Niloofar, FOROUZESH FLORA. SARS-COV-2: History, Genetics, and Treatment. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2021;23(5 (147) ):666-669. Available from: https://sid.ir/paper/691890/en

    IEEE: Copy

    Niloofar Agharezaee, and FLORA FOROUZESH, “SARS-COV-2: History, Genetics, and Treatment,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 23, no. 5 (147) , pp. 666–669, 2021, [Online]. Available: https://sid.ir/paper/691890/en

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