IMMUNO- MODULATORY AND ANTI-TUMOR EFFECTS OF CUMINUM CYMINUM ESSENTIAL OIL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOLEYMANI NEDA; DANESHMANDI S.; SATARI MORTEZA; POURFATH ELAH A.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2011 | Volume:13 | Issue:4 (53) Page(s): 22-29

Download Full-Text

Persian Verion

View:

1,250

Download:

Cites:

Information Journal Paper

Title

IMMUNO- MODULATORY AND ANTI-TUMOR EFFECTS OF CUMINUM CYMINUM ESSENTIAL OIL

Author(s)

SOLEYMANI NEDA | DANESHMANDI S. | SATARI MORTEZA | POURFATH ELAH A.A. | Issue Writer Certificate

Keywords

ANTITUMORQ3

CUMINUM CYMINUMQ3

MACROPHAGEQ3

MTT ASSAYQ3

NITRIC OXIDEQ2

Abstract

Background: Correct use of CUMINUM CYMINUM and finding its different applications in medicine and industry necessitates a more clear understanding of this medicinal plant. This study deals with identifying the effects of the essential oil of this herbal plant on MACROPHAGEs and tumor cell lines.Materials and Methods:Cuminum cyminum essential oil was extracted from its fruit, and its effects on peritoneal MACROPHAGEs and LPS stimulated MACROPHAGEs were examined. MTT ASSAY was done for evaluation of MACROPHAGEs viability and the amount of NITRIC OXIDE (NO) in culture supernant was measured by Griess Reagent. WEHI-164 mice fibrosarcoma cell line was cultured with different concentrations of CUMINUM CYMINUM and cytotoxicity level was evaluated by MTT ASSAY.Results: The viability of MACROPHAGEs and also, the amount of NO production in 50 and 500 mg/ml CUMINUM CYMINUM essential oil was lower than that of the control group (p<0.001). MTT ASSAY showed that CUMINUM CYMINUM essential oil in 50 and 500 mg/ml concentrations significantly inhibits tumor cells growth (p<0.001).Conclusion: CUMINUM CYMINUM essential oil by having immune-modulatory properties can be used in treatment of many inflammatory and immunologic disorders. Also, it can be used as a therapeutic or complementary agent in tumor therapy.

Cites

Effect of Recombinant Helicobacter Outer Membrane Protein H (HopH) on Nitric Oxide Production by Peripheral Macrophage in BALB/c Mice

References

No record.

Cite

APA: Copy

SOLEYMANI, NEDA, DANESHMANDI, S., SATARI, MORTEZA, & POURFATH ELAH, A.A.. (2011). IMMUNO- MODULATORY AND ANTI-TUMOR EFFECTS OF CUMINUM CYMINUM ESSENTIAL OIL. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 13(4 (53)), 22-29. SID. https://sid.ir/paper/69213/en

Vancouver: Copy

SOLEYMANI NEDA, DANESHMANDI S., SATARI MORTEZA, POURFATH ELAH A.A.. IMMUNO- MODULATORY AND ANTI-TUMOR EFFECTS OF CUMINUM CYMINUM ESSENTIAL OIL. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2011;13(4 (53)):22-29. Available from: https://sid.ir/paper/69213/en

IEEE: Copy

NEDA SOLEYMANI, S. DANESHMANDI, MORTEZA SATARI, and A.A. POURFATH ELAH, “IMMUNO- MODULATORY AND ANTI-TUMOR EFFECTS OF CUMINUM CYMINUM ESSENTIAL OIL,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 13, no. 4 (53), pp. 22–29, 2011, [Online]. Available: https://sid.ir/paper/69213/en

Related Journal Papers