An Unusual Presentation of Choriocarcinoma: A Case Report with a Long Latent Period

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Najib Fatemeh Sadat; Shiravani Zahra; Hajisafari Mojgan; Moradi Alamdarloo Shaghayegh; Hashemi Atefe; RAZAVI BEHNAZ; MOKHTARI MARAL

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Journal: International Journal of Cancer Management Year:2021 | Volume:14 | Issue:3 Page(s): 0-0

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Title

An Unusual Presentation of Choriocarcinoma: A Case Report with a Long Latent Period

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Keywords

Choriocacinoma

Gynecologic Diseases

Gynecologic Neoplasm

Case Reports

Abstract

Introduction: Choriocarcinoma (CC) is a rare malignant tumor of trophoblastic tissue. This tends to invade rapidly to the vasculature and metastasis to the lung, vagina, brain, and liver. CC can present with a variety of manifestations, such as hemoptysis, gastrointestinal (GI) bleeding, and abnormal uterine bleeding. Commonly, the latent period to the development of CC is not more than 1 year after the antecedent molar or normal pregnancy. In this report, the patient developed CC about 32 months after her previous known pregnancy. We reported a rare case of gestational CC that occurred about 32 months after her antecedent pregnancy. Case Presentation: A 21-year-old admitted in shock with abnormal uterine bleeding, pain, and lower abdominal pain. The patient had one previous cesarean section 32 months prior to admission. The vaginal examination demonstrated a fused solid cervical mass with an irregular border measuring about 7 7 cm. In further workup, there was evidence of a 103 94 89 mmmass with the hemorrhagic area and central necrosis in the middle and lower segments of the uterus and cervix. The patient underwent a total abdominal hysterectomy and left side salpingo-oophorectomy. The diagnosis of CC was made after microscopic examination. Conclusions: There are few Case Reports of choriocarcinoma with more than a year latent period after antecedent pregnancy. The strongest hypothesis is having asymptomatic pregnancy during the period between the last pregnancy and the development of CC. However, the possibility of non-gestational choriocarcinoma in such cases should be considered. Treatment with a single-or multiple-agent chemotherapy regimen should be immediately initiated after diagnosis in these cases.

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APA: Copy

Najib, Fatemeh Sadat, Shiravani, Zahra, Hajisafari, Mojgan, Moradi Alamdarloo, Shaghayegh, Hashemi, Atefe, RAZAVI, BEHNAZ, & MOKHTARI, MARAL. (2021). An Unusual Presentation of Choriocarcinoma: A Case Report with a Long Latent Period. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), 14(3), 0-0. SID. https://sid.ir/paper/692796/en

Vancouver: Copy

Najib Fatemeh Sadat, Shiravani Zahra, Hajisafari Mojgan, Moradi Alamdarloo Shaghayegh, Hashemi Atefe, RAZAVI BEHNAZ, MOKHTARI MARAL. An Unusual Presentation of Choriocarcinoma: A Case Report with a Long Latent Period. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION)[Internet]. 2021;14(3):0-0. Available from: https://sid.ir/paper/692796/en

IEEE: Copy

Fatemeh Sadat Najib, Zahra Shiravani, Mojgan Hajisafari, Shaghayegh Moradi Alamdarloo, Atefe Hashemi, BEHNAZ RAZAVI, and MARAL MOKHTARI, “An Unusual Presentation of Choriocarcinoma: A Case Report with a Long Latent Period,” INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), vol. 14, no. 3, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/692796/en

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