IDENTIFICATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACTS FROM THE AERIAL PARTS OF BALLOTA PLATYLOMA RECH. F.

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SEYEDALIPOUR BEGHER; HASANI ALI; EBRAHIMZADEH MOHAMMADALI; MOHSENI MOJTABA

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Journal: Journal of Arak University Medical Sciences Year:2016 | Volume:18 | Issue:11 (104) Page(s): 34-43

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Title

IDENTIFICATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACTS FROM THE AERIAL PARTS OF BALLOTA PLATYLOMA RECH. F.

Author(s)

SEYEDALIPOUR BEGHER | HASANI ALI | EBRAHIMZADEH MOHAMMADALI | MOHSENI MOJTABA | Issue Writer Certificate

Keywords

ANTIBACTERIAL ACTIVITYQ2

BALLOTA PLATYLOMA RECH. F.Q2

ESSENTIAL OILQ1

GERMACRENE DQ2

METHANOLIC EXTRACTSQ2

Abstract

Background: Lamiaceae family has about 200 genuses and 4000 species. The majority of species of the family have essence that was used for nutritional, cosmetic and pharmaceutical industry. The aim of this study was to investigate the chemical composition of ESSENTIAL OIL from aerial parts of Bollota platyloma and ANTIBACTERIAL ACTIVITY of it.Materials and Methods: In this experimental study, study Ballota platyloma, belonging to lamiaceae family and entomic of iran, was collected from Versk region in Mazandaran provinc. ESSENTIAL OIL from aerial parts was obtained by hydro distillation method by using Clevenger apparatus. GC/MS analysis of ESSENTIAL OIL was carried out to identify major volatile constituents. Extraction was prepared by maceration method. ANTIBACTERIAL ACTIVITY of METHANOLIC EXTRACTS against Pseudomonas aeruginosa, Bacillus subtilis, Stapylococcus aureus, Escherichia coli was investigated by disc diffusion method and minimal inhibitory concentration (MIC) method.Results: Results showed that GC/MS analysis of the ESSENTIAL OIL confirms the presence of 24 constituents in Ballota platyloma. The main constituents were Hexadecanoic Acid (40.03%), GERMACRENE D (26.6%) and Beta Caryophylene (4.76%). The results indicated that methanolic extract of Ballota platyloma possessed ANTIBACTERIAL ACTIVITY. Among the aforementioned bacteria, the highest ANTIBACTERIAL ACTIVITY was seen against S. aureus and the lowest activity against P. aeruginosa.Conclusion: The findings of the present study showed that the major component of oil essential was germacrene-D and methanolic extract from the aerial parts of BALLOTA PLATYLOMA RECH. F. possess anti-bacterial effects. Thus, in order to find the underlying mechanism of this activity, further research should be carried out.

Cites

THE EFFECT OF SILYBIN ENCAPSULATED IN NANOPARTICLES ON OPRM GENE EXPRESSION IN DRUG RESISTANT ISOLATES OF PSEUDOMONAS AERUGINOSA

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APA: Copy

SEYEDALIPOUR, BEGHER, HASANI, ALI, EBRAHIMZADEH, MOHAMMADALI, & MOHSENI, MOJTABA. (2016). IDENTIFICATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACTS FROM THE AERIAL PARTS OF BALLOTA PLATYLOMA RECH. F.. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 18(11 (104)), 34-43. SID. https://sid.ir/paper/69416/en

Vancouver: Copy

SEYEDALIPOUR BEGHER, HASANI ALI, EBRAHIMZADEH MOHAMMADALI, MOHSENI MOJTABA. IDENTIFICATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACTS FROM THE AERIAL PARTS OF BALLOTA PLATYLOMA RECH. F.. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2016;18(11 (104)):34-43. Available from: https://sid.ir/paper/69416/en

IEEE: Copy

BEGHER SEYEDALIPOUR, ALI HASANI, MOHAMMADALI EBRAHIMZADEH, and MOJTABA MOHSENI, “IDENTIFICATION OF THE CHEMICAL COMPOSITION OF ESSENTIAL OIL AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF METHANOLIC EXTRACTS FROM THE AERIAL PARTS OF BALLOTA PLATYLOMA RECH. F.,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 18, no. 11 (104), pp. 34–43, 2016, [Online]. Available: https://sid.ir/paper/69416/en

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