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Information Journal Paper

Title

EXPRESSION OF THE MIR‐133 AND BCL‐2 COULD BE AFFECTED BY SWIMMING TRAINING IN THE HEART OF OVARIECTOMIZED RATS

Pages

  381-387

Abstract

 Objective (s): The beneficial and more potent role of exercise to prevent HEART apoptosis in ovariectomized rats has been known. The aim of this study was to examine the effects of SWIMMING TRAINING on cardiac expression of BCL‐2, and MIR‐133 levels and glycogen changes in the myocyte.Materials and Methods: Forty animals were separated into four groups as control, sham, OVARIECTOMY (OVX) and ovariectomized group with 8 weeks SWIMMING TRAINING (OVX.E). Training effects were evaluated by measuring lipid profiles, BCL‐2 and MIR‐133 expression levels in the cardiac tissue.Grafts were analyzed by reverse transcription–olymerase chain reaction for BCL‐2 mRNA and MIR‐133 and by Western blot for BCL‐2 protein.Results: OVARIECTOMY down‐regulated BCL‐2 and MIR‐133 expression levels in the cardiac tissue, and SWIMMING TRAINING up‐regulated their expression significantly (P<0.05).Conclusion: Our results showed that regular exercise as a physical replacement therapy could prevent and improve the effects of estrogen deficiency in the cardia.

Cites

References

Cite

APA: Copy

HABIBI, PARISA, ALIHEMMATI, ALIREZA, NOURAZAR, ALIREZA, YOUSEFI, HADI, MORTAZAVI, SAFIEH, & AHMADIASL, NASSER. (2016). EXPRESSION OF THE MIR?133 AND BCL?2 COULD BE AFFECTED BY SWIMMING TRAINING IN THE HEART OF OVARIECTOMIZED RATS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 19(4), 381-387. SID. https://sid.ir/paper/696080/en

Vancouver: Copy

HABIBI PARISA, ALIHEMMATI ALIREZA, NOURAZAR ALIREZA, YOUSEFI HADI, MORTAZAVI SAFIEH, AHMADIASL NASSER. EXPRESSION OF THE MIR?133 AND BCL?2 COULD BE AFFECTED BY SWIMMING TRAINING IN THE HEART OF OVARIECTOMIZED RATS. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2016;19(4):381-387. Available from: https://sid.ir/paper/696080/en

IEEE: Copy

PARISA HABIBI, ALIREZA ALIHEMMATI, ALIREZA NOURAZAR, HADI YOUSEFI, SAFIEH MORTAZAVI, and NASSER AHMADIASL, “EXPRESSION OF THE MIR?133 AND BCL?2 COULD BE AFFECTED BY SWIMMING TRAINING IN THE HEART OF OVARIECTOMIZED RATS,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 19, no. 4, pp. 381–387, 2016, [Online]. Available: https://sid.ir/paper/696080/en

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