FREQUENCY OF HUMAN LEUKOCYTE ANTIGENS (HLA) CLASS-I AND II IN ARAKIAN PATIENTS WITH INSULIN DEPENDENT DIABETES MELLITUS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MOSAYEBI GHASEM; GHAZNAVIRAD E.A.; FANI A.; MOAZENI S.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download Full-Text

Persian Verion

View:

840

Download:

Cites:

Information Journal Paper

Title

FREQUENCY OF HUMAN LEUKOCYTE ANTIGENS (HLA) CLASS-I AND II IN ARAKIAN PATIENTS WITH INSULIN DEPENDENT DIABETES MELLITUS

Author(s)

MOSAYEBI GHASEM | GHAZNAVIRAD E.A. | FANI A. | MOAZENI S.A. | Issue Writer Certificate

Keywords

INSULIN DEPENDENT DIABETES MELLITUSQ3

HUMAN LEUKOCYTE ANTIGENSQ4

Abstract

Introduction: INSULIN DEPENDENT DIABETES MELLITUS (IDDM) or type 1 diabetes is created by autoimmune destruction of insulin-producing beta cells of the pancreas in genetically susceptible individuals. The relationship between HUMAN LEUKOCYTE ANTIGENS (HLA) associated factors and susceptibility to IDDM disease, was reported by several investigators. Association with different HLA types depends also on the studied populations. The aim of the present study was to determine HLA antigens which represent a high susceptibility to develop the IDDM disease in this area.Materials and Methods: In this study, the prevalence of HLA class-I and II antigens has been determined in 31 Arakian patients with IDDM and 57 normal healthy controls with similar ethnic background and from the same geographical area. The typing of HLA antigens was carried out using standard microlymphocytotoxicity method.Results: A significantly higher frequency of HLA-A2, A3, B21, DR3 and DQ2 were found in IDDM cases compared to the controls. In contrast, HLA-DR2, DR7 and B53 were represented at a somewhat higher frequency in controls compared to the IDDM patients.Conclusion: These results indicate that HLA-A2, A3, B21, DR3 and DQ2 antigens contribute to susceptibility to IDDM independently and HLA-DR2, DR7 and B53 antigens maybe associated with prevention of IDDM in Arakian patients.

Cites

No record.

References

No record.

Cite

APA: Copy

MOSAYEBI, GHASEM, GHAZNAVIRAD, E.A., FANI, A., & MOAZENI, S.A.. (2005). FREQUENCY OF HUMAN LEUKOCYTE ANTIGENS (HLA) CLASS-I AND II IN ARAKIAN PATIENTS WITH INSULIN DEPENDENT DIABETES MELLITUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 8(3 (32)), 42-49. SID. https://sid.ir/paper/69722/en

Vancouver: Copy

MOSAYEBI GHASEM, GHAZNAVIRAD E.A., FANI A., MOAZENI S.A.. FREQUENCY OF HUMAN LEUKOCYTE ANTIGENS (HLA) CLASS-I AND II IN ARAKIAN PATIENTS WITH INSULIN DEPENDENT DIABETES MELLITUS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2005;8(3 (32)):42-49. Available from: https://sid.ir/paper/69722/en

IEEE: Copy

GHASEM MOSAYEBI, E.A. GHAZNAVIRAD, A. FANI, and S.A. MOAZENI, “FREQUENCY OF HUMAN LEUKOCYTE ANTIGENS (HLA) CLASS-I AND II IN ARAKIAN PATIENTS WITH INSULIN DEPENDENT DIABETES MELLITUS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 8, no. 3 (32), pp. 42–49, 2005, [Online]. Available: https://sid.ir/paper/69722/en

Related Journal Papers