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Information Journal Paper

Title

Asparagus Officinalis: An Herbal Candidate for an Intraoral Healing Mouthwash

Pages

  31-36

Abstract

 Objectives Asparagus officinalis (A. officinalis) extract has several bioactive ingredients. This study assessed the healing effects of A. officinalis methanolic extract. Methods In this experimental study, after preparing the methanolic extract of A. officinalis with a concentration of 100 ⁄ , its bioactive ingredients were determined using high-performance liquid chromatography (HPLC) and then its cytotoxicity was assessed using the methyl thiazolyl tetrazolium (MTT) assay. Five experimental groups with 25 samples were assessed as follows: (I)human gingival fibroblast(HGFs) cultured in high-glucose Dulbecco’ s modified Eagle’ s medium (DMEM), (II) same as group Ibut with 10 μ g/mL methanolic extract of A. officinalis, (III) same as group Ibut with 25μ g/mL methanolic extract of A. officinalis, (IV) same as group Ibut with 50 μ g/mL methanolic extract of A. officinalis, and (V)same as group Ibut with 100μ g/mL methanolic extract of A. officinalis. Cell motility in the control group and group Vwas examined quantitatively using the cell scratch assay at 24 h. We used one-way ANOVA and t-test to analyzethe cytotoxicity of A. officinalis extract and the motility of HGFs, respectively. Results The MTT assay showed no significant difference in cell viability among the experimental groups (P=0. 07). A remarkable cellular wound closure equal to 60. 85% was noted after 24 h. Conclusion The methanolic extract of A. officinalis with a concentration of 100 μ g⁄ mL showed significant healing effects on an experimental scratch setup of HGFs.

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    APA: Copy

    Shamsoddin, Erfan, BASHASH, DAVOOD, ZAREI, MALEK, & HOUSHMAND, BEHZAD. (2020). Asparagus Officinalis: An Herbal Candidate for an Intraoral Healing Mouthwash. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 38(1), 31-36. SID. https://sid.ir/paper/697321/en

    Vancouver: Copy

    Shamsoddin Erfan, BASHASH DAVOOD, ZAREI MALEK, HOUSHMAND BEHZAD. Asparagus Officinalis: An Herbal Candidate for an Intraoral Healing Mouthwash. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2020;38(1):31-36. Available from: https://sid.ir/paper/697321/en

    IEEE: Copy

    Erfan Shamsoddin, DAVOOD BASHASH, MALEK ZAREI, and BEHZAD HOUSHMAND, “Asparagus Officinalis: An Herbal Candidate for an Intraoral Healing Mouthwash,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 38, no. 1, pp. 31–36, 2020, [Online]. Available: https://sid.ir/paper/697321/en

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