Clinical Proﬁ le and Predictors of Outcome for Pediatric Scrub Typhus at a Tertiary Care Hospital

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Muthukrishnan Kiruthika; Tarikere Shruthi; Sivaraman Rajakumar Padur; Sankaranarayanan Shuba; Prabaharan Krithika; Kothandam Balaji Thiruvengadam

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Journal: Archives of Pediatric Infectious Diseases Year:2021 | Volume:9 | Issue:1 Page(s): 0-0

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Title

Clinical Proﬁ le and Predictors of Outcome for Pediatric Scrub Typhus at a Tertiary Care Hospital

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Keywords

Pediatric Scrub Typhus

Predictors of Outcome

Complication

Abstract

Background: Scrub typhus is an important cause of acute undiﬀ erentiated fever. It is currently one of the most covert re-emerging infections and the most common rickettsial infection caused by Orientia tsutsugamushi. Untreated cases can have mortality rates as high as 30-35%. Objectives: This study was done to study demographical data, clinical proﬁ le, and Predictors of Outcome for scrub typhus in children who were admitted to our institution, a tertiary care hospital in south India. Methods: In this retrospective study, children diagnosed with scrub typhus based on IgM enzyme-linked immunosorbent assay (ELISA), between January 2012 and June 2019 were included. Detailed history, clinical examination ﬁ ndings, laboratory proﬁ le, Complications, and outcome were analyzed. Results: A total of 120 patients were identiﬁ ed, of whom 84 (42 males-and 42 females) cases satisﬁ ed the inclusion criteria and were analyzed. About 80 (95%) cases had a complete recovery, whereas 4 patients (5%) died of multiple Complications. Hypotension, hypoxia, altered sensorium, hypoalbuminemia, elevated liver enzymes, azotemia, and deranged coagulation on admission were considered as poor Predictors of Outcome for scrub typhus. Conclusions: Pediatric Scrub Typhus is a common infection and should be suspected in cases with fever for more than 5 days and non-speciﬁ c signs and symptoms. Early detection and timely management lead to a higher recovery rate. Hypotension, hypoxia, azotemia, altered sensorium, and bleeding manifestations on admission were associated with unfavorable outcomes.

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APA: Copy

Muthukrishnan, Kiruthika, Tarikere, Shruthi, Sivaraman, Rajakumar Padur, Sankaranarayanan, Shuba, Prabaharan, Krithika, & Kothandam, Balaji Thiruvengadam. (2021). Clinical Proﬁ le and Predictors of Outcome for Pediatric Scrub Typhus at a Tertiary Care Hospital. ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES, 9(1), 0-0. SID. https://sid.ir/paper/698671/en

Vancouver: Copy

Muthukrishnan Kiruthika, Tarikere Shruthi, Sivaraman Rajakumar Padur, Sankaranarayanan Shuba, Prabaharan Krithika, Kothandam Balaji Thiruvengadam. Clinical Proﬁ le and Predictors of Outcome for Pediatric Scrub Typhus at a Tertiary Care Hospital. ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES[Internet]. 2021;9(1):0-0. Available from: https://sid.ir/paper/698671/en

IEEE: Copy

Kiruthika Muthukrishnan, Shruthi Tarikere, Rajakumar Padur Sivaraman, Shuba Sankaranarayanan, Krithika Prabaharan, and Balaji Thiruvengadam Kothandam, “Clinical Proﬁ le and Predictors of Outcome for Pediatric Scrub Typhus at a Tertiary Care Hospital,” ARCHIVES OF PEDIATRIC INFECTIOUS DISEASES, vol. 9, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/698671/en

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