INVESTIGATION OF INTERACTION BETWEEN DEFEROXAMINE AND LOW FREQUENCY ELECTROMAGNETIC FIELD ON ANGIOGENESIS IN CHICK EMBRYO

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DASHTIZADEH ATENA

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Journal Paper

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Journal: Zahedan Journal of Research in Medical Sciences Year:2015 | Volume:17 | Issue:2 Page(s): 0-0

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Title

INVESTIGATION OF INTERACTION BETWEEN DEFEROXAMINE AND LOW FREQUENCY ELECTROMAGNETIC FIELD ON ANGIOGENESIS IN CHICK EMBRYO

Author(s)

DASHTIZADEH ATENA | Issue Writer Certificate

Keywords

ANGIOGENESIS

DEFEROXAMINE

ELECTROMAGNETIC FIELD

CHORIOALLANTOIC MEMBRANE

Abstract

Background: DEFEROXAMINE (DFO) is an iron chelator. In the present research, thesynergic effects of DEFEROXAMINE and ELECTROMAGNETIC FIELD (with 50 H frequency and 100Gauss intensity) on ANGIOGENESIS of chick CHORIOALLANTOIC MEMBRANE were investigated.Materials and Methods: In this experimental study 80 fertilized egg used and randomlydivided 8 group: control group, laboratory control groups of 1 and 2, experimental group 1(treatment with ELECTROMAGNETIC FIELD), 2 and 3 (treatment with DEFEROXAMINE 10, 100µmol, respectively), 4 and 5 (treatment both DEFEROXAMINE 10 and 100 µmol respectivelyand ELECTROMAGNETIC FIELD). On 8th day of incubation, 2 and 4 groups were incubated with10 µL DEFEROXAMINE and for 3 and 5 groups were incubated with 10 µL DEFEROXAMINE 100µmol. On 10th day, 1, 4 and 5 groups were put in ELECTROMAGNETIC FIELD. On 12th day, thenumber and length of vessels in all samples was measured by Image J software. Data wereanalyzed by SPSS-19, ANOVA and t-test.Results: The mean number and length of vessels in the control and experimental cases didnot show any significant differences. Comparison between mean number of vessels in thecontrol and group 2, 3, 4, 5 showed a significant decrease (p<0.05) and groups 2 and 4 wasshowed a significant decrease in the mean length of vessels compared with the controls(p<0.05).Conclusion: Using DEFEROXAMINE with low frequency ELECTROMAGNETIC FIELD (50 Hz and100 G) cause inhibition of ANGIOGENESIS in chick embryo CHORIOALLANTOIC MEMBRANE.

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APA: Copy

DASHTIZADEH, ATENA. (2015). INVESTIGATION OF INTERACTION BETWEEN DEFEROXAMINE AND LOW FREQUENCY ELECTROMAGNETIC FIELD ON ANGIOGENESIS IN CHICK EMBRYO. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 17(2), 0-0. SID. https://sid.ir/paper/700302/en

Vancouver: Copy

DASHTIZADEH ATENA. INVESTIGATION OF INTERACTION BETWEEN DEFEROXAMINE AND LOW FREQUENCY ELECTROMAGNETIC FIELD ON ANGIOGENESIS IN CHICK EMBRYO. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2015;17(2):0-0. Available from: https://sid.ir/paper/700302/en

IEEE: Copy

ATENA DASHTIZADEH, “INVESTIGATION OF INTERACTION BETWEEN DEFEROXAMINE AND LOW FREQUENCY ELECTROMAGNETIC FIELD ON ANGIOGENESIS IN CHICK EMBRYO,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 17, no. 2, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/700302/en

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