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Information Journal Paper

Title

Cerebrospinal Fluid and Spinal Anesthesia Parameters in Healthy Individuals versus Opium-addict Patients during Lower Limb Surgery

Pages

  11-17

Abstract

 Background: Studies have reported lower pain threshold, Spinal Anesthesia duration, and level of sensory block in addicts compared to non-addict patients undergoing Spinal Anesthesia for surgery. Moreover, blood gas and cerebroSpinal fluid (CSF) were likely to be affected as well. The aim in the present study is to evaluate CSF and Spinal parameters in addict versus non-addict patients during lower limb surgery. Methods: In this case-control study, 22 Opium addicts and 22 sex-and age-matched non-addicts undergoing lower limb surgery under Spinal Anesthesia were included. The CSF parameters, venous blood gas (VBG), and sensory and motor block findings were compared between the groups. Findings: The addict and non-addict patients were similar regarding CSF and blood gas parameters except higher pH in VBG (7. 39 ± 0. 06 vs. 7. 33 ± 0. 11, P = 0. 030) and CSF (7. 39 ± 0. 06 vs. 7. 33 ± 0. 11, P = 0. 030) for addict patients. The addict patients had significantly later onset of sensory block (5. 72 ± 1. 57 vs. 3. 16 ± 0. 93 minutes, P < 0. 001) and shorter motor block duration (137. 72 ± 11. 51 vs. 149. 09 ± 14. 44 minutes, P = 0. 006), with no significant difference in the sensory block duration and motor block onset. Conclusion: Addict patients have delayed onset of sensory block with shorter duration of motor block and lower sensory block level. Among the blood gas and CSF markers, only pH was significantly higher in addict patients, needing further evaluations; however, it seems that addiction has no significant effect on these parameters.

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    APA: Copy

    DERAKHSHAN, POOYA, IMANI, FARNAD, SEYED SIAMDOUST, SEYED ALIREZA, Garousi, Sorour, & NOURI, NASRIN. (2020). Cerebrospinal Fluid and Spinal Anesthesia Parameters in Healthy Individuals versus Opium-addict Patients during Lower Limb Surgery. ADDICTION AND HEALTH, 12(1 ), 11-17. SID. https://sid.ir/paper/701884/en

    Vancouver: Copy

    DERAKHSHAN POOYA, IMANI FARNAD, SEYED SIAMDOUST SEYED ALIREZA, Garousi Sorour, NOURI NASRIN. Cerebrospinal Fluid and Spinal Anesthesia Parameters in Healthy Individuals versus Opium-addict Patients during Lower Limb Surgery. ADDICTION AND HEALTH[Internet]. 2020;12(1 ):11-17. Available from: https://sid.ir/paper/701884/en

    IEEE: Copy

    POOYA DERAKHSHAN, FARNAD IMANI, SEYED ALIREZA SEYED SIAMDOUST, Sorour Garousi, and NASRIN NOURI, “Cerebrospinal Fluid and Spinal Anesthesia Parameters in Healthy Individuals versus Opium-addict Patients during Lower Limb Surgery,” ADDICTION AND HEALTH, vol. 12, no. 1 , pp. 11–17, 2020, [Online]. Available: https://sid.ir/paper/701884/en

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