Survival Rate and Prognostic Factors Among Patients Undergoing Hematopoietic Stem Cell Transplantation: Using the Joint Model

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Arab Borzu Zahra; KHADEMBASHI NAGHMEH; HAJIFATHALI ABBAS; Baghestani Aahmadreza; ROSHANDEL ELHAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Cancer Management Year:2021 | Volume:14 | Issue:3 Page(s): 0-0

Download Full-Text

View:

Download:

122

Cites:

Information Journal Paper

Title

Survival Rate and Prognostic Factors Among Patients Undergoing Hematopoietic Stem Cell Transplantation: Using the Joint Model

Author(s)

Keywords

Bayesian Approach

Disease

Survival

Hematopoietic Stem Cells

Abstract

Background: Hematopoietic stem cell transplantation (HSCT) is the most effective of all hematologic malignancies treatments, resulting in a significant improvement in Survival rate. Objectives: This study aimed at determining the Survival rate and factors affecting the Survival in patients undergoing hematopoietic stem cell transplantation, using the joint model. Methods: This study was a retrospective cohort study, used for collecting data from patients with hematopoietic malignancies who underwent hematopoietic stem cell transplantation in Taleghani Hospital (Shahid Beheshti University of Medical Sciences), Tehran, Iran during the years 2007 and 2015 and were followed up till 2017. A Bayesian joint model of longitudinal and Survival was chosen, using Win Bugs software. Results: A total of 395 patients were enrolled. The median overall Survival was 6. 3 years (95% CI (5. 86, 6. 76)). Eighty-one patients had died. The obtained results from this study manifested that age (HR: 1. 02, 95% CI: (1. 002, 1. 04)) and pre-transplantation relapse (HR = 1. 64, 95% CI: (1. 09, 2. 4)) have incremental impact on death after transplantation, while malignancy type (NHL (HR: 0. 33, 95%CI: (0. 152, 0. 73)) andAML(HR: 0. 62, 95% CI: (0. 29, 0. 7)) are also effective in reducing death after transplantation. Similarly, the correlation index between longitudinal and Survival models proved to be significant (HR: 0. 6, 95% CI: (0. 0802, 0. 37)). Conclusions: This study showed that age, per-transplantation relapse, and malignancy type are the effective factors in the Survival rate. Moreover, the link parameter between longitudinal response (WBC) and the Survival indicated that an increase in WBC count leads to a decrease in the death risk.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

Arab Borzu, Zahra, KHADEMBASHI, NAGHMEH, HAJIFATHALI, ABBAS, Baghestani, Aahmadreza, & ROSHANDEL, ELHAM. (2021). Survival Rate and Prognostic Factors Among Patients Undergoing Hematopoietic Stem Cell Transplantation: Using the Joint Model. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), 14(3), 0-0. SID. https://sid.ir/paper/702336/en

Vancouver: Copy

Arab Borzu Zahra, KHADEMBASHI NAGHMEH, HAJIFATHALI ABBAS, Baghestani Aahmadreza, ROSHANDEL ELHAM. Survival Rate and Prognostic Factors Among Patients Undergoing Hematopoietic Stem Cell Transplantation: Using the Joint Model. INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION)[Internet]. 2021;14(3):0-0. Available from: https://sid.ir/paper/702336/en

IEEE: Copy

Zahra Arab Borzu, NAGHMEH KHADEMBASHI, ABBAS HAJIFATHALI, Aahmadreza Baghestani, and ELHAM ROSHANDEL, “Survival Rate and Prognostic Factors Among Patients Undergoing Hematopoietic Stem Cell Transplantation: Using the Joint Model,” INTERNATIONAL JOURNAL OF CANCER MANAGEMENT (IRANIAN JOURNAL OF CANCER PREVENTION), vol. 14, no. 3, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/702336/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops