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Information Journal Paper

Title

CELLULAR APOPTOSIS AND BLOOD BRAIN BARRIER PERMEABILITY CHANGES IN THE PREINCUBATED CHICKEN EMBRYO’S BRAIN BY EFFECT OF ELECTROMAGNETIC FIELDS

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  0-0

Abstract

 Background: ELECTROMAGNETIC FIELDs (EMF) have teratogenic effects during theembryonic development. In current study, histopathological and physiological effectsof sinusoidal EMF on the BRAIN were investigated. We sought to determine theapoptosis level and changes in blood BRAIN barrier permeability in BRAIN tissue of preincubated white leghorn hen eggs in the field of EMF.Materials and Methods: In this experimental study, 300 healthy, fresh, and fertilizedeggs (55-65 g) were divided into experimental (3 groups, N=50), control (N=75) andsham (N=75) groups. Experimental eggs (inside the coil) were exposed to 3 differentintensities of 1.33, 2.66 and 7.32 mT and sham groups were also located inside thesame coil but with no exposure, for 24 hrs before incubation. Control, sham andexperimental groups were incubated in an incubator (38±0.5ºC, 60% humidity). BRAINsof 14 day old CHICKEN EMBRYOs of all groups were removed, fixed in formalin (10%), stained with H & E and TUNEL, apoptotic cells were studied under light microscope.BRAINs of other embryos were prepared for scanning electron microscope. By injectionsof Evans blue, any possible changes in BRAIN vessels were also investigated.Results: Our results showed ELECTROMAGNETIC FIELDs have toxic effects on cell organellesand cell membranes. EMF would increase the level of cellular APOPTOSIS in the BRAIN.They also would tear up the blood vessels. Thereafter, they would affect thepermeability of blood BRAIN barrier of exposed CHICKEN EMBRYOs.Conclusion: These findings suggest that ELECTROMAGNETIC FIELDs induce differentdegrees of BRAIN damages in CHICKEN EMBRYOs BRAIN tissue.

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    APA: Copy

    Kalantari, Sima. (2015). CELLULAR APOPTOSIS AND BLOOD BRAIN BARRIER PERMEABILITY CHANGES IN THE PREINCUBATED CHICKEN EMBRYO’S BRAIN BY EFFECT OF ELECTROMAGNETIC FIELDS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 17(2), 0-0. SID. https://sid.ir/paper/703939/en

    Vancouver: Copy

    Kalantari Sima. CELLULAR APOPTOSIS AND BLOOD BRAIN BARRIER PERMEABILITY CHANGES IN THE PREINCUBATED CHICKEN EMBRYO’S BRAIN BY EFFECT OF ELECTROMAGNETIC FIELDS. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2015;17(2):0-0. Available from: https://sid.ir/paper/703939/en

    IEEE: Copy

    Sima Kalantari, “CELLULAR APOPTOSIS AND BLOOD BRAIN BARRIER PERMEABILITY CHANGES IN THE PREINCUBATED CHICKEN EMBRYO’S BRAIN BY EFFECT OF ELECTROMAGNETIC FIELDS,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 17, no. 2, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/703939/en

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