THE ROLE OF AEROBIC EXERCISE ON PAIN BY HISTAMINE RECEPTORS USING FORMALIN TEST IN MICE

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HEJAZIAN E.; SADEGHIAN M.R.; HEJAZIAN S.H.

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Journal: Journal of Rafsanjan University of Medical Sciences Year:2016 | Volume:15 | Issue:1 Page(s): 17-26

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Title

THE ROLE OF AEROBIC EXERCISE ON PAIN BY HISTAMINE RECEPTORS USING FORMALIN TEST IN MICE

Author(s)

HEJAZIAN E. | SADEGHIAN M.R. | HEJAZIAN S.H. | Issue Writer Certificate

Keywords

AEROBIC EXERCISEQ2

PAINQ2

HISTAMINE RECEPTORSQ1

FORMALINQ3

ANALGESIAQ3

Abstract

Background and Objectives: AEROBIC EXERCISE or cardio is defined as a physical exercise that causes high oxygen consumption compared to the rest and conducted to increased cardiorespiratory intensity. Different substances, can inhibit PAIN occurred through opioids, histaminergic, and cholinergic receptors. This study was done to determine the role of AEROBIC EXERCISE in PAIN by HISTAMINE RECEPTORS using FORMALIN test in miceMaterials and Methods: In this experimental study, by use of FORMALIN test, the analgesic effect has been used in three groups of control, test one and test two and by ranitidine which is a histamine receptores inhibitor, the analgesic effect of AEROBIC EXERCISE and the role of HISTAMINE RECEPTORS were investigated. For this purpose by use of mean score of PAIN and two way Anova and repeated major in every 5 minute; regarding, FORMALIN test, as a standard PAIN inducing, was used.Results: Our result indicated that subcoutanous injection of FORMALIN to the paw of the animal significantly (P<0.05) reduced the PAIN score in group of exercise while the mean score of PAIN in group that first recievedranitidine (as histamine receptores blocker) increased and was not significantly differentConclusion: The analgesic effects of AEROBIC EXERCISE may be induced by HISTAMINE RECEPTORS.

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APA: Copy

HEJAZIAN, E., SADEGHIAN, M.R., & HEJAZIAN, S.H.. (2016). THE ROLE OF AEROBIC EXERCISE ON PAIN BY HISTAMINE RECEPTORS USING FORMALIN TEST IN MICE. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, 15(1), 17-26. SID. https://sid.ir/paper/70790/en

Vancouver: Copy

HEJAZIAN E., SADEGHIAN M.R., HEJAZIAN S.H.. THE ROLE OF AEROBIC EXERCISE ON PAIN BY HISTAMINE RECEPTORS USING FORMALIN TEST IN MICE. JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES[Internet]. 2016;15(1):17-26. Available from: https://sid.ir/paper/70790/en

IEEE: Copy

E. HEJAZIAN, M.R. SADEGHIAN, and S.H. HEJAZIAN, “THE ROLE OF AEROBIC EXERCISE ON PAIN BY HISTAMINE RECEPTORS USING FORMALIN TEST IN MICE,” JOURNAL OF RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES, vol. 15, no. 1, pp. 17–26, 2016, [Online]. Available: https://sid.ir/paper/70790/en

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