ASSESSMENT OF THE MAXIMUM UPTAKE TIME OF 99MTC-DMSA IN RENAL SCINTIGRAPHY IN RAT

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TANHA KAVEH; Fatemikia Hossein; ASSADI MAJID; SEYEDABADI MOHAMMAD

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Journal: IRANIAN JOURNAL OF NUCLEAR MEDICINE Year:2017 | Volume:25 | Issue:2 (SERIAL NUMBER 49) Page(s): 110-114

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Information Journal Paper

Title

ASSESSMENT OF THE MAXIMUM UPTAKE TIME OF 99MTC-DMSA IN RENAL SCINTIGRAPHY IN RAT

Author(s)

TANHA KAVEH | Fatemikia Hossein | ASSADI MAJID | SEYEDABADI MOHAMMAD | Issue Writer Certificate

Keywords

SMALL ANIMAL IMAGING

RENAL SCINTIGRAPHY

MAXIMUM UPTAKE TIME

99MTC-DMSA

Abstract

Introduction: The optimal imaging time of a radionuclide scintigraphy is the time at which the organ of interest has the maximum uptake of the injected radionuclide. This study was performed to investigate the MAXIMUM UPTAKE TIME of 99mTc-DMSA in rat renal scan.Methods: RENAL SCINTIGRAPHY was performed with 3 mCi of 99mTc-DMSA. Planar images were acquired every 20 minutes for 8 hours post-injection using a small-animal SPECT.Results: Activity and the count rate per pixel (CRPP) of the kidneys peaked 1 h post-injection, plateaued for about 1 h, and declined time-dependently. Kidney to background ratio (KBR) reached to 61.7% at 1 h after injection and remained almost constant afterwards.Conclusion: The kidneys had maximum emission and CRPP between 1 to 2 h after 99mTc-DMSA injection, whereas there was no significant difference between the KBRs after 1 h. Our results showed that image acquisition of 1-2 h post-injection is recommended for RENAL SCINTIGRAPHY with DMSA in rat.

Cites

Serological, pathological, and scintigraphic assessment of Hemiscorpius lepturus effects on renal dysfunction in rats

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APA: Copy

TANHA, KAVEH, Fatemikia, Hossein, ASSADI, MAJID, & SEYEDABADI, MOHAMMAD. (2017). ASSESSMENT OF THE MAXIMUM UPTAKE TIME OF ^99MTC-DMSA IN RENAL SCINTIGRAPHY IN RAT. IRANIAN JOURNAL OF NUCLEAR MEDICINE, 25(2 (SERIAL NUMBER 49)), 110-114. SID. https://sid.ir/paper/709170/en

Vancouver: Copy

TANHA KAVEH, Fatemikia Hossein, ASSADI MAJID, SEYEDABADI MOHAMMAD. ASSESSMENT OF THE MAXIMUM UPTAKE TIME OF ^99MTC-DMSA IN RENAL SCINTIGRAPHY IN RAT. IRANIAN JOURNAL OF NUCLEAR MEDICINE[Internet]. 2017;25(2 (SERIAL NUMBER 49)):110-114. Available from: https://sid.ir/paper/709170/en

IEEE: Copy

KAVEH TANHA, Hossein Fatemikia, MAJID ASSADI, and MOHAMMAD SEYEDABADI, “ASSESSMENT OF THE MAXIMUM UPTAKE TIME OF ^99MTC-DMSA IN RENAL SCINTIGRAPHY IN RAT,” IRANIAN JOURNAL OF NUCLEAR MEDICINE, vol. 25, no. 2 (SERIAL NUMBER 49), pp. 110–114, 2017, [Online]. Available: https://sid.ir/paper/709170/en

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