Hydroxychloroquine-Induced Hyperpigmentation: A Case Report

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Talaschian Mona; SADEGHI ANAHITA; PAKZAD SARA

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Journal Paper

Paper Information

Journal: Case Reports in Clinical Practice Year:2020 | Volume:5 | Issue:3 Page(s): 89-91

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Information Journal Paper

Title

Hydroxychloroquine-Induced Hyperpigmentation: A Case Report

Author(s)

Talaschian Mona | SADEGHI ANAHITA | PAKZAD SARA | Issue Writer Certificate

Keywords

Hydroxychloroquine

Hyperpigmentation

Drug side effect

Rheumatoid arthritis

Abstract

Antimalarial agents, including chloroquine and Hydroxychloroquine, have been used for the treatment of various rheumatoid diseases and skin diseases because of their anti-inflammatory and immune-modulating properties. Cutaneous adverse effects such as exacerbation of psoriasis, pruritus, and Hyperpigmentation have been reported as side-effects of antimalarial drugs. In this case, we report a middle-aged man with a history of Rheumatoid arthritis who was treated with non-steroidal anti-inflammatory drugs and Hydroxychloroquine. He complained of Hyperpigmentation of the face after one year of initiating the Hydroxychloroquine. It was discontinued and methotrexate was started. Skin biopsy was confirmed drug reaction. After more than 10 years of follow up, his skin discoloration had not been improved.

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APA: Copy

Talaschian, Mona, SADEGHI, ANAHITA, & PAKZAD, SARA. (2020). Hydroxychloroquine-Induced Hyperpigmentation: A Case Report. CASE REPORTS IN CLINICAL PRACTICE, 5(3), 89-91. SID. https://sid.ir/paper/709629/en

Vancouver: Copy

Talaschian Mona, SADEGHI ANAHITA, PAKZAD SARA. Hydroxychloroquine-Induced Hyperpigmentation: A Case Report. CASE REPORTS IN CLINICAL PRACTICE[Internet]. 2020;5(3):89-91. Available from: https://sid.ir/paper/709629/en

IEEE: Copy

Mona Talaschian, ANAHITA SADEGHI, and SARA PAKZAD, “Hydroxychloroquine-Induced Hyperpigmentation: A Case Report,” CASE REPORTS IN CLINICAL PRACTICE, vol. 5, no. 3, pp. 89–91, 2020, [Online]. Available: https://sid.ir/paper/709629/en

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