THE EFFICACY OF LEVOFLOXACIN-BASED TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION AFTER FAILURE WITH CLARITHROMYCIN-CONTAINING REGIMENS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FAKHERI HAFEZ; BARI ZOHREH; TAGHVAEI TARANG; HOSSEINI VAHID; MALEKI IRADJ; VALIZADEH SEYED MOHAMMAD; Kazemi Arash

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: GOVARESH JOURNAL Year:2018 | Volume:22 | Issue:4 Page(s): 261-265

Download Full-Text

View:

237

Download:

141

Cites:

Information Journal Paper

Title

THE EFFICACY OF LEVOFLOXACIN-BASED TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION AFTER FAILURE WITH CLARITHROMYCIN-CONTAINING REGIMENS

Author(s)

Keywords

HELICOBACTER PYLORI

ERADICATION

LEVOFLOXACIN

SECOND-LINE

CLARITHROMYCIN

Abstract

Background:Clinical trials and meta-analyses have reported about 20% failure rates in first-line HELICOBACTER PYLORI (H. pylori) ERADICATION.This reflects the need for effective SECOND-LINE ERADICATION regimens.Materials and Methods:61 patients with H. pylori infection who had failed previous non-bismuth CLARITHROMYCIN-containing first line therapies entered thestudy. They were given a 14-day LEVOFLOXACIN-containing triple regimen consisted of pantoprazole 40 mg, amoxicillin 1gr, and LEVOFLOXACIN500mg, each given twice daily. Eight weeks after the treatment, H. pylori ERADICATION was assessed by 14C-urea breath test.Results:All patients completed the study. The ERADICATION rate was 91.8% (95% confidence interval = 84.9% – 98.6%) by both intentionto treat and per-protocol analyses. Side effects of therapy were reported by eight patients (13.1%), but they were severe in onlytwo patients (3.2%).Conclusion:According to the high H. pylori ERADICATION rate and the very low rate of severe adverse effects, LEVOFLOXACIN-containing tripletherapy seems to be a suitable SECOND-LINE option in case of previous failure by CLARITHROMYCIN-containing therapies. We suggestfurther studies with shorter duration of treatment or lower dose of LEVOFLOXACIN.

Cites

No record.

References

Cite

APA: Copy

FAKHERI, HAFEZ, BARI, ZOHREH, TAGHVAEI, TARANG, HOSSEINI, VAHID, MALEKI, IRADJ, VALIZADEH, SEYED MOHAMMAD, & Kazemi, Arash. (2018). THE EFFICACY OF LEVOFLOXACIN-BASED TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION AFTER FAILURE WITH CLARITHROMYCIN-CONTAINING REGIMENS. GOVARESH JOURNAL, 22(4 ), 261-265. SID. https://sid.ir/paper/713858/en

Vancouver: Copy

FAKHERI HAFEZ, BARI ZOHREH, TAGHVAEI TARANG, HOSSEINI VAHID, MALEKI IRADJ, VALIZADEH SEYED MOHAMMAD, Kazemi Arash. THE EFFICACY OF LEVOFLOXACIN-BASED TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION AFTER FAILURE WITH CLARITHROMYCIN-CONTAINING REGIMENS. GOVARESH JOURNAL[Internet]. 2018;22(4 ):261-265. Available from: https://sid.ir/paper/713858/en

IEEE: Copy

HAFEZ FAKHERI, ZOHREH BARI, TARANG TAGHVAEI, VAHID HOSSEINI, IRADJ MALEKI, SEYED MOHAMMAD VALIZADEH, and Arash Kazemi, “THE EFFICACY OF LEVOFLOXACIN-BASED TRIPLE THERAPY FOR HELICOBACTER PYLORI ERADICATION AFTER FAILURE WITH CLARITHROMYCIN-CONTAINING REGIMENS,” GOVARESH JOURNAL, vol. 22, no. 4 , pp. 261–265, 2018, [Online]. Available: https://sid.ir/paper/713858/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops