THE PROGNOSTIC VALUE OF STRESS/REST GATED MYOCARDIAL PERFUSION SPECT IN PATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASE

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FAZLINEZHAD AFSOON; GHADERI FERESHTEH; MADANI SANI MORTEZA; MOMENNEZHAD MAHDI; DABBAGH KAKHKI VAHID REZA; GHOLOOBI ARASH

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Journal: IRANIAN JOURNAL OF NUCLEAR MEDICINE Year:2017 | Volume:25 | Issue:2 (SERIAL NUMBER 49) Page(s): 115-121

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Title

THE PROGNOSTIC VALUE OF STRESS/REST GATED MYOCARDIAL PERFUSION SPECT IN PATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASE

Author(s)

Keywords

MYOCARDIAL PERFUSION SPECT

GATED SPECT

CARDIAC EVENTS

PROGNOSIS

EJECTION FRACTION

TRANSIENT ISCHEMIC DILATION

Abstract

Introduction: Gated MYOCARDIAL PERFUSION SPECT has diagnostic and prognostic values in coronary artery disease (CAD). We tried to determine prognostic values of the left ventricular perfusion & functional indices as well as transient left ventricular dilation (TID) derived from gated MYOCARDIAL PERFUSION SPECT.Methods: 1820 patients who underwent gated MYOCARDIAL PERFUSION SPECT (Gated SPECT) were studied. The summed stress score (SSS), summed rest score (SRS) and summed difference score (SDS) were calculated. CARDIAC EVENTS considered as nonfatal myocardial infarction, cardiac death, Coronary Care Unit admission and revascularization. Mean follow-up period after GATED SPECT was 23±10 months.Results: 1599 patients didn’t have any events, while from remaining 221, six patients had an acute MI, 90 patients had CCU admission, 42 patients underwent revascularization and 84 patients died. There was statistically significant difference in the CARDIAC EVENTS based on age, sex, SSS, SRS, SDS, TPD, TID, left ventricular volumes and LVEF. Multivariable Cox regression analysis showed the most and independent predictors of CARDIAC EVENTS are age (P=0.001), SSS (P=0.01) and history of coronary angiography (CA) (P=0.01). History of CA had a greater than 4.4 fold increased incidence of a cardiac event. With increase in SSS for 1 score, 1.4 times and with increase one year in age 1.4 fold increase in future cardiac event were seen.Conclusion: There was a strong association between future CARDIAC EVENTS and clinical history, SSS, SRS, SDS, TPD, TID, left ventricular volumes and LVEF. The most and independent predictors were age, SSS and history of CA.

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APA: Copy

FAZLINEZHAD, AFSOON, GHADERI, FERESHTEH, MADANI SANI, MORTEZA, MOMENNEZHAD, MAHDI, DABBAGH KAKHKI, VAHID REZA, & GHOLOOBI, ARASH. (2017). THE PROGNOSTIC VALUE OF STRESS/REST GATED MYOCARDIAL PERFUSION SPECT IN PATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASE. IRANIAN JOURNAL OF NUCLEAR MEDICINE, 25(2 (SERIAL NUMBER 49)), 115-121. SID. https://sid.ir/paper/715188/en

Vancouver: Copy

FAZLINEZHAD AFSOON, GHADERI FERESHTEH, MADANI SANI MORTEZA, MOMENNEZHAD MAHDI, DABBAGH KAKHKI VAHID REZA, GHOLOOBI ARASH. THE PROGNOSTIC VALUE OF STRESS/REST GATED MYOCARDIAL PERFUSION SPECT IN PATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASE. IRANIAN JOURNAL OF NUCLEAR MEDICINE[Internet]. 2017;25(2 (SERIAL NUMBER 49)):115-121. Available from: https://sid.ir/paper/715188/en

IEEE: Copy

AFSOON FAZLINEZHAD, FERESHTEH GHADERI, MORTEZA MADANI SANI, MAHDI MOMENNEZHAD, VAHID REZA DABBAGH KAKHKI, and ARASH GHOLOOBI, “THE PROGNOSTIC VALUE OF STRESS/REST GATED MYOCARDIAL PERFUSION SPECT IN PATIENTS WITH KNOWN OR SUSPECTED CORONARY ARTERY DISEASE,” IRANIAN JOURNAL OF NUCLEAR MEDICINE, vol. 25, no. 2 (SERIAL NUMBER 49), pp. 115–121, 2017, [Online]. Available: https://sid.ir/paper/715188/en

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