Determination of antibiotic resistance and minimum inhibitory concentration of meropenem and imipenem growth in Klebsiella strains isolated from urinary tract infection in Shahrekord educational hospitals

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Kakian Farshad; Zamzad Behnam; GHOLIPOUR ABOLFAZL; Zamanzad Kiarash

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Shahrekord University of Medical Sciences Year:2019 | Volume:21 | Issue:2 Page(s): 80-85

Download Full-Text

View:

210

Download:

161

Cites:

Information Journal Paper

Title

Determination of antibiotic resistance and minimum inhibitory concentration of meropenem and imipenem growth in Klebsiella strains isolated from urinary tract infection in Shahrekord educational hospitals

Author(s)

Kakian Farshad | Zamzad Behnam | GHOLIPOUR ABOLFAZL | Zamanzad Kiarash | Issue Writer Certificate

Keywords

Klebsiella

Antibiotic resistance

Meropenem

Imipenem

Abstract

Background and aims: Klebsiella is an opportunistic organism that is the cause of severe diseases such as pneumonia, septicemia, and urinary tract infections (UTIs). In addition, high Antibiotic resistance has challenged the treatment of this bacterium. However, carbapenem antibiotics are considered as the therapeutic agents for selecting the treatment of penicillin-and cephalosporin-resistant gram-negative bacterial infections. The present study aimed to determine the resistance and minimum inhibitory concentration (MIC) of Meropenem and Imipenem. Methods: A total of 80 Klebsiella spp isolated from UTIs were collected in various educational wards (i. e., urology, obstetrics, and gynecology, as well as the units of infectious diseases, internal medicine, and intensive care) in different hospitals of Shahrekord. The isolates were then identified by using biochemical tests. Further, disc diffusion method was employed to determine the Antibiotic resistance. Furthermore, MIC was estimated by the Epsilon-test strip. Moreover, P=Q=0. 50, an error of 0. 05, and an accuracy of 0. 11 were considered for determining the sample size (n = 80). Results: Based on the results of disc diffusion method, 24 strains were resistant to Meropenem and Imipenem. Additionally, the MIC was 24 (30%) by the E-test. In addition, 24 isolates had a MIC of ≥ 4 μ g/mL for Meropenem and Imipenem and thus were resistant while 18 isolates were found to have a MIC of 1≤ MIC<4 μ g/mL and therefore, were considered semi-sensitive (P < 0. 001). Conclusion: In general, Klebsiella strains were found to be resistant to Meropenem and Imipenem. Therefore, rapid and accurate identification of these strains and the selection of appropriate antibiotics can help quickly eradicate the infections caused by these bacteria. Accordingly, a waste of time, the consumption of medication, or even an increased resistance are prevented.

Cites

No record.

References

No record.

Cite

APA: Copy

Kakian, Farshad, Zamzad, Behnam, GHOLIPOUR, ABOLFAZL, & Zamanzad, Kiarash. (2019). Determination of antibiotic resistance and minimum inhibitory concentration of meropenem and imipenem growth in Klebsiella strains isolated from urinary tract infection in Shahrekord educational hospitals. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, 21(2), 80-85. SID. https://sid.ir/paper/718263/en

Vancouver: Copy

Kakian Farshad, Zamzad Behnam, GHOLIPOUR ABOLFAZL, Zamanzad Kiarash. Determination of antibiotic resistance and minimum inhibitory concentration of meropenem and imipenem growth in Klebsiella strains isolated from urinary tract infection in Shahrekord educational hospitals. JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;21(2):80-85. Available from: https://sid.ir/paper/718263/en

IEEE: Copy

Farshad Kakian, Behnam Zamzad, ABOLFAZL GHOLIPOUR, and Kiarash Zamanzad, “Determination of antibiotic resistance and minimum inhibitory concentration of meropenem and imipenem growth in Klebsiella strains isolated from urinary tract infection in Shahrekord educational hospitals,” JOURNAL OF SHAHREKORD UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 2, pp. 80–85, 2019, [Online]. Available: https://sid.ir/paper/718263/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops