Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa

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Parsa Mina; AHMADI MALAHAT; Dastmalchi Habib; Tehrani Aliasghar

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Paper Information

Journal: MEDICAL LABORATORY JOURNAL Year:2017 | Volume:11 | Issue:6 Page(s): 7-11

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Title

Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa

Author(s)

Parsa Mina | AHMADI MALAHAT | Dastmalchi Habib | Tehrani Aliasghar | Issue Writer Certificate

Keywords

Nanoparticles

Arginine

Anti-Bacterial Agents

Pseudomonas aeruginosa

Abstract

Background and Objectives: Nowadays, the prevalence of multidrug-resistant pathogens such as Pseudomonas aeruginosa is increasing worldwide. Many studies have been seeking new treatment strategies to treat infections caused by these microorganisms. Silver Nanoparticles (AgNPs) along with L-Arginine have significant antimicrobial effects and could be used as alternatives for ineffective drugs. Methods: In this study, the antibacterial activity of AgNPs, L-Arginine and various concentrations of AgNPs along with L-Arginine (12. 5 and 25 mg/ml) were investigated against P. aeruginosa PAO1 using the broth macrodilution method. Results: Minimum inhibitory concentration of AgNPs, L-Arginine and AgNPs combined with 25 and 12. 5 mg/ml L-Arginine was 15. 6 μ g/ml, 25 mg/ml, 1. 9 μ g/ml and 3. 9 μ g/ml, respectively. Minimum bactericidal concentration of AgNPs, L-Arginine and AgNPs combined with 25 and 12. 5 mg/ml L-Arginine was 31. 2 μ g/ml, 50 mg/ml, 3. 9 μ g/ml and 7. 8 μ g/ml, respectively. Conclusion: Our study suggests that AgNPs along with L-Arginine can be used as an alternative antibacterial agent against P. aeruginosa, and might be useful for treatment of wound infections.

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APA: Copy

Parsa, Mina, AHMADI, MALAHAT, Dastmalchi, Habib, & Tehrani, Aliasghar. (2017). Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa. MEDICAL LABORATORY JOURNAL, 11(6), 7-11. SID. https://sid.ir/paper/718759/en

Vancouver: Copy

Parsa Mina, AHMADI MALAHAT, Dastmalchi Habib, Tehrani Aliasghar. Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa. MEDICAL LABORATORY JOURNAL[Internet]. 2017;11(6):7-11. Available from: https://sid.ir/paper/718759/en

IEEE: Copy

Mina Parsa, MALAHAT AHMADI, Habib Dastmalchi, and Aliasghar Tehrani, “Antibacterial Effect of Silver Nanoparticles along with L-Arginine against P. aeruginosa,” MEDICAL LABORATORY JOURNAL, vol. 11, no. 6, pp. 7–11, 2017, [Online]. Available: https://sid.ir/paper/718759/en

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