Effects of left prefrontal transcranial direct current stimulation on the acquisition of contextual and cued fear memory

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABBASI SHAHSANAM; NASEHI MOHAMMAD; SOLEIMANPOUR LICHAEI HAMID REZA; ZARRINDAST MOHAMMAD REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2017 | Volume:20 | Issue:6 Page(s): 623-630

Download Full-Text

View:

194

Download:

116

Cites:

Information Journal Paper

Title

Effects of left prefrontal transcranial direct current stimulation on the acquisition of contextual and cued fear memory

Author(s)

ABBASI SHAHSANAM | NASEHI MOHAMMAD | SOLEIMANPOUR LICHAEI HAMID REZA | ZARRINDAST MOHAMMAD REZA | Issue Writer Certificate

Keywords

Fear

Memory

Prefrontal cortex

tDCS

Abstract

Objective(s): Behavioral and neuroimaging studies have shown that transcranial direct current stimulation, as a non-invasive neuromodulatory technique, beyond regional effects can modify functionally interconnected remote cortical and subcortical areas. In this study, we hypothesized that the induced changes in cortical excitability following the application of cathodal or anodal tDCS over the left frontal cortex as pre-training would affect functional connectivity in resting-state circuits of Fear Memory and consequently could improve or disturb the acquisition of Fear Memory. Materials and Methods: In order to evaluate the polarity-dependent effects of tDCS on the acquisition of Fear Memory and the functional connectivity, we applied left prefrontal anodal or cathodal stimulation at 200 μ A for one session to healthy mice for the durations of 20 and 30 min prior to Fear conditioning. Results: Our results revealed that the administration of left prefrontal anodal (for both 20 and 30 min durations) and cathodal (at 30 min duration) tDCS impaired the acquisition of both contextual and cued Fear Memory. In addition, we did not observe a direct correlation between stimulation duration and the efficacy of tDCS on the acquisition of contextual and cued Fear Memory. Conclusion: In this study, the impairments of both contextual and cued Memory further confirmed the previous studies reporting that the administration of transcranial stimulation would affect the activity of deeper structures like amygdala and hippocampus as the main components of the Fear Memory circuit in acquisition, storage, and expression of the Memory.

Cites

The Involvement of D1 and D2 Dopamine Receptors in the Restoration Effect of Left Frontal Anodal, but not Cathodal, tDCS on Streptozocin-Induced Amnesia

References

No record.

Cite

APA: Copy

ABBASI, SHAHSANAM, NASEHI, MOHAMMAD, SOLEIMANPOUR LICHAEI, HAMID REZA, & ZARRINDAST, MOHAMMAD REZA. (2017). Effects of left prefrontal transcranial direct current stimulation on the acquisition of contextual and cued fear memory. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 20(6), 623-630. SID. https://sid.ir/paper/719737/en

Vancouver: Copy

ABBASI SHAHSANAM, NASEHI MOHAMMAD, SOLEIMANPOUR LICHAEI HAMID REZA, ZARRINDAST MOHAMMAD REZA. Effects of left prefrontal transcranial direct current stimulation on the acquisition of contextual and cued fear memory. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2017;20(6):623-630. Available from: https://sid.ir/paper/719737/en

IEEE: Copy

SHAHSANAM ABBASI, MOHAMMAD NASEHI, HAMID REZA SOLEIMANPOUR LICHAEI, and MOHAMMAD REZA ZARRINDAST, “Effects of left prefrontal transcranial direct current stimulation on the acquisition of contextual and cued fear memory,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 20, no. 6, pp. 623–630, 2017, [Online]. Available: https://sid.ir/paper/719737/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops