Emerging insights into the biology of metastasis: A review article

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IRANI SOUSSAN

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Journal Paper

Paper Information

Journal: Iranian Journal of Basic Medical Sciences Year:2019 | Volume:22 | Issue:8 Page(s): 833-847

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Title

Emerging insights into the biology of metastasis: A review article

Author(s)

IRANI SOUSSAN | Issue Writer Certificate

Keywords

Biomarkers

Circulating cells

Exosomes

Extracellular matrix

Metastasis

MicroRNAs

Neoplasms

Stem cells

Abstract

Metastasis means the dissemination of the cancer cells from one organ to another which is not directly connected to the primary site. Metastasis has a crucial role in the prognosis of cancer patients. A few theories, different types of cell and several molecular pathways have been proposed to explain the mechanism of Metastasis. In this work, the related articles in the limited period of time, 2000– mid-2018 were reviewed, through search in PubMed, Google Scholar and Scopus database. The articles published in the last two decades related to the biology of cancer Metastasis were selected and the most important factors were discussed. Metastasis is critical factor to predict survival in patients with advanced cancer and prognosis determines the treatment plan. Many different cell types and various signaling pathways control the metastatic process. Metastasis is a multistep process. Many signaling pathways and molecules are involved in Metastasis. Increasing knowledge about the mechanism of Metastasis can help in finding the promising targets of cancer therapy.

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APA: Copy

IRANI, SOUSSAN. (2019). Emerging insights into the biology of metastasis: A review article. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 22(8), 833-847. SID. https://sid.ir/paper/723605/en

Vancouver: Copy

IRANI SOUSSAN. Emerging insights into the biology of metastasis: A review article. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2019;22(8):833-847. Available from: https://sid.ir/paper/723605/en

IEEE: Copy

SOUSSAN IRANI, “Emerging insights into the biology of metastasis: A review article,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 22, no. 8, pp. 833–847, 2019, [Online]. Available: https://sid.ir/paper/723605/en

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