Doppler assessment of children with liver cirrhosis and portal hypertension in comparison with a healthy control group: An analytical cross‑ sectional study

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Riahinezhad Maryam; REZAEI MOHAMMADREZA; SANEIAN HOSEIN; FARGHADANI MARYAM

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Paper Information

Journal: JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS) Year:2018 | Volume:23 | Issue:5 Page(s): 0-0

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Title

Doppler assessment of children with liver cirrhosis and portal hypertension in comparison with a healthy control group: An analytical cross‑ sectional study

Author(s)

Riahinezhad Maryam | REZAEI MOHAMMADREZA | SANEIAN HOSEIN | FARGHADANI MARYAM | Issue Writer Certificate

Keywords

Cirrhosis

Doppler ultrasonography

pediatrics

portal hypertension

portal vein

Abstract

Background: Doppler ultrasonography (Doppler US) plays an important role in evaluating patients with liver Cirrhosis. This study aims to investigate the hemodynamic alterations of hepatic artery and portal vein among children with liver Cirrhosis and portal hypertension (esophageal varices). Materials and Methods: We conducted an analytical cross‑ sectional study in Imam Hossein Children’ s Hospital, Isfahan, Iran, in 2016. A number of 33 cirrhotic children with or without esophageal varices were selected through convenience sampling method to be compared with 19 healthy children as controls using color and spectral Doppler US. Results: portal vein mean velocities were 15. 03 ± 7. 3 cm/s in cirrhotics, 16. 47 ± 6. 4 cm/s in controls (P = 0. 51), 11. 6 ± 4. 7 cm/s in patients with varices, and 17. 9 ± 7. 3 cm/s in patients without varices (P = 0. 015). Mean diameters of caudate lobe, portal vein, and splenic vein, as well as the mean values of liver and spleen span, were significantly higher in cirrhotic children. The frequency of flow reversal (hepatofugal flow) was not detected significantly different in cirrhotics. Peak systolic velocity, end diastolic velocity, pulsatility index, and resistive index for hepatic artery as well as liver vascular index were not significantly different in cirrhotics in comparison with controls. Conclusion: Alterations in Doppler parameters of portal vein including diameter and velocity may be the helpful indicators of liver Cirrhosis and esophageal varices in children, respectively. Parameters of hepatic artery may not differentiate children with liver Cirrhosis.

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APA: Copy

Riahinezhad, Maryam, REZAEI, MOHAMMADREZA, SANEIAN, HOSEIN, & FARGHADANI, MARYAM. (2018). Doppler assessment of children with liver cirrhosis and portal hypertension in comparison with a healthy control group: An analytical cross‑ sectional study. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), 23(5), 0-0. SID. https://sid.ir/paper/724572/en

Vancouver: Copy

Riahinezhad Maryam, REZAEI MOHAMMADREZA, SANEIAN HOSEIN, FARGHADANI MARYAM. Doppler assessment of children with liver cirrhosis and portal hypertension in comparison with a healthy control group: An analytical cross‑ sectional study. JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS)[Internet]. 2018;23(5):0-0. Available from: https://sid.ir/paper/724572/en

IEEE: Copy

Maryam Riahinezhad, MOHAMMADREZA REZAEI, HOSEIN SANEIAN, and MARYAM FARGHADANI, “Doppler assessment of children with liver cirrhosis and portal hypertension in comparison with a healthy control group: An analytical cross‑ sectional study,” JOURNAL OF RESEARCH IN MEDICAL SCIENCES (JRMS), vol. 23, no. 5, pp. 0–0, 2018, [Online]. Available: https://sid.ir/paper/724572/en

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