مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

297
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

259
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

AN ANSWER TO COLON CANCER TREATMENT BY MESENCHYMAL STEM CELL ORIGINATED FROM ADIPOSE TISSUE

Pages

  465-468

Abstract

 Objective (s): COLON CANCER is risen up with its complex mechanism that directly impacts on its treatment as well as its common prevalence. Mesenchymal STEM CELLS (MSCs) have been considered as a therapeutic candidate for conventional disease including cancer. In this research, we have focused on apoptotic effects of adipose tissue-derived MSCs in COLON CANCER.Materials and Methods: MSCs were obtained from adipose tissue and characterized by Flowcytometer using suitable antibodies. MSCs, HT-29, HCT-116, RKO and healthy cell line MRC5 were cultured by different seeding procedure. After cell viability assay, changes in caspase 3 enzyme activity and the level of phosphatidylserine were measured.Results: For cell viability assay, a 48 hr incubation period was chosen to seed all cells together. There was a 1.36-fold decrease in caspase 3 enzyme activity by co-treatment of RKO and MSCs in addition to 2.02-fold decrease in HT-29 and MSCs co-treatment, and 1.103-fold increase in HCT-116 and MSCs. The results demonstrated that HCT-116 led to the highest rate of apoptotic CELL DEATH (7.5%) compared with other cells.Conclusion: We suggest that MSCs might remain a new treatment option for cancer by its differentiation and repair capacity.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    IPLIK, ELIF SINEM, ERTUGRUL, BARIS, KOZANOGLU, ILKNUR, BARAN, YUSUF, & CAKMAKOGLU, BEDIA. (2018). AN ANSWER TO COLON CANCER TREATMENT BY MESENCHYMAL STEM CELL ORIGINATED FROM ADIPOSE TISSUE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 21(5), 465-468. SID. https://sid.ir/paper/727657/en

    Vancouver: Copy

    IPLIK ELIF SINEM, ERTUGRUL BARIS, KOZANOGLU ILKNUR, BARAN YUSUF, CAKMAKOGLU BEDIA. AN ANSWER TO COLON CANCER TREATMENT BY MESENCHYMAL STEM CELL ORIGINATED FROM ADIPOSE TISSUE. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2018;21(5):465-468. Available from: https://sid.ir/paper/727657/en

    IEEE: Copy

    ELIF SINEM IPLIK, BARIS ERTUGRUL, ILKNUR KOZANOGLU, YUSUF BARAN, and BEDIA CAKMAKOGLU, “AN ANSWER TO COLON CANCER TREATMENT BY MESENCHYMAL STEM CELL ORIGINATED FROM ADIPOSE TISSUE,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 21, no. 5, pp. 465–468, 2018, [Online]. Available: https://sid.ir/paper/727657/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button