COMPARISON OF ORAL AND SUBLINGUAL MISOPROSTOL IN INDUCTION OF DELIVERY

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NIROUMANESH SHIRIN; TALEBZADEH NOORI Z.; HOSSEINPOUR M.

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Title

COMPARISON OF ORAL AND SUBLINGUAL MISOPROSTOL IN INDUCTION OF DELIVERY

Author(s)

NIROUMANESH SHIRIN | TALEBZADEH NOORI Z. | HOSSEINPOUR M. | Issue Writer Certificate

Keywords

INDUCTION OF LABORQ3

ORAL AND SUBLINGUAL MISOPROSTOLQ3

TERM DELIVERYQ3

Abstract

BACKGROUND & OBJECTIVE: Delivery is believed to be physiologic process that the majority of pregnant women experience it successfully; however its probable complications may occur suddenly. Early admission in delivery unit is important especially in the cases with known fetal or maternal risk factors. The aim of this study was to compare oral and sublingual (50µg) misoprostol in induction of TERM DELIVERY.METHODS: This clinical trial study was performed on 150 pregnant women with gestational age ≥37 weeks that admitted for INDUCTION OF LABOR. Having inclusion criteria, patients included in this study obtained NST (Non Stress Test) and received 50 microgram oral or sublingual randomly. Then two methods were compared with regard to maternal and fetal complication, induction to delivery interval, drug dose and the rate of cesarean delivery, Proportions were compared by t- test and fisher's exact tests. FINDINGS: From 150 cases, 75 patients were assigned to oral misoprostol and 75 patients were assigned to sublingual misoprostol group. Mean of time from induction to delivery in oral group was 8.53±3.55 hours and in sublingual group was 7.05±3.16 hours (p=0.008). Maternal and fetal outcome in each group showed significant difference but labor complication, drug dose, the rate of cesarean delivery and women who needed to oxytoxin did not show significant difference.CONCLUSION: The results showed that sublingual route of misoprostol administration has greater efficacy in labor induction and additionally was better tolerated by pregnant women.

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APA: Copy

NIROUMANESH, SHIRIN, TALEBZADEH NOORI, Z., & HOSSEINPOUR, M.. (2006). COMPARISON OF ORAL AND SUBLINGUAL MISOPROSTOL IN INDUCTION OF DELIVERY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 8(5 (33)), 20-25. SID. https://sid.ir/paper/73104/en

Vancouver: Copy

NIROUMANESH SHIRIN, TALEBZADEH NOORI Z., HOSSEINPOUR M.. COMPARISON OF ORAL AND SUBLINGUAL MISOPROSTOL IN INDUCTION OF DELIVERY. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2006;8(5 (33)):20-25. Available from: https://sid.ir/paper/73104/en

IEEE: Copy

SHIRIN NIROUMANESH, Z. TALEBZADEH NOORI, and M. HOSSEINPOUR, “COMPARISON OF ORAL AND SUBLINGUAL MISOPROSTOL IN INDUCTION OF DELIVERY,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 8, no. 5 (33), pp. 20–25, 2006, [Online]. Available: https://sid.ir/paper/73104/en

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