PROBING WITH AND WITHOUT MITOMYCIN C IN THE TREATMENT OF LACRIMAL OBSTRUCTION

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MIKANIKI E.; RASOULINEZHAD S.A.

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Journal Paper

Paper Information

Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2007 | Volume:9 | Issue:1 (36) Page(s): 20-23

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Information Journal Paper

Title

PROBING WITH AND WITHOUT MITOMYCIN C IN THE TREATMENT OF LACRIMAL OBSTRUCTION

Author(s)

MIKANIKI E. | RASOULINEZHAD S.A. | Issue Writer Certificate

Keywords

LACRIMAL OBSTRUCTIONQ3

PROBINGQ3

MITOMYCIN-CQ3

TREATMENTQ3

Abstract

Background and objective: LACRIMAL OBSTRUCTION is common and its TREATMENT is problematic. PROBING is being used for TREATMENT of this condition but failure of therapy is relatively high. The purpose of this study was to compare the efficacy of PROBING versus the same procedure with intraoperative injection of MITOMYCIN-C in the TREATMENT of LACRIMAL OBSTRUCTION.Methods: this interventional study was conducted on 120 eyes from 106 subjects who referred to the department of ophthalmology of babol medical university from september 2004 to september 2006. These cases randomly divided into two groups (60 eyes in each group). The first group was treated by PROBING and the second group was treated by PROBING and intraoperative injection of 1 ml mitomycin C, 0.2 mg/ml. After TREATMENT these cases were followed after one week, 1 month, 3 months, 6 months and one year later. Outcome of TREATMENT in these two groups were compared.Findings: the mean age of patients in group one (45 females and 15 males) was 38±12 years and in group 2 (38 females and 12 males) was 35±14.2 years (p>0.05). One month after TREATMENT, cure rate in group one was 55% and in group 2 was 96.6% (p=0.000). After one year, cure rate was seen in 40% cases in group 1 and in 95% cases in group 2 (p=0.000). Mean survival of success of therapy after one year in PROBING group was 5.7 months (95% CI, 4.33 to 7.07) and in PROBING with mitomycin C group was 11.52 months (95% CI, 10.97 to 12) (p=0.0001(.Conclusion: the results of this study showed that PROBING and intraoperative injection of mitomycin C is more efficacious than PROBING alone for TREATMENT of LACRIMAL OBSTRUCTION.

Cites

EFFICACY OF DACRYOCYSTORHINOSTOMY WITH CATHETER INSERTION OR BODKIN TUBE IN THE TREATMENT OF NASOLACRIMAL OBSTRUCTION

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APA: Copy

MIKANIKI, E., & RASOULINEZHAD, S.A.. (2007). PROBING WITH AND WITHOUT MITOMYCIN C IN THE TREATMENT OF LACRIMAL OBSTRUCTION. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 9(1 (36)), 20-23. SID. https://sid.ir/paper/73187/en

Vancouver: Copy

MIKANIKI E., RASOULINEZHAD S.A.. PROBING WITH AND WITHOUT MITOMYCIN C IN THE TREATMENT OF LACRIMAL OBSTRUCTION. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2007;9(1 (36)):20-23. Available from: https://sid.ir/paper/73187/en

IEEE: Copy

E. MIKANIKI, and S.A. RASOULINEZHAD, “PROBING WITH AND WITHOUT MITOMYCIN C IN THE TREATMENT OF LACRIMAL OBSTRUCTION,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 9, no. 1 (36), pp. 20–23, 2007, [Online]. Available: https://sid.ir/paper/73187/en

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