TOXICITY EFFECTS OF ALUMINIUM CHLORIDE ON UTERUS AND PLACENTA OF PREGNANT MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KARIMPOUR A.; TORABI ZADEH J.; SADUGHI M.; SADEGHI DARABI S.S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2005 | Volume:7 | Issue:1 (25) Page(s): 22-27

Download Full-Text

Persian Verion

View:

1,244

Download:

Cites:

Information Journal Paper

Title

TOXICITY EFFECTS OF ALUMINIUM CHLORIDE ON UTERUS AND PLACENTA OF PREGNANT MICE

Author(s)

KARIMPOUR A. | TORABI ZADEH J. | SADUGHI M. | SADEGHI DARABI S.S. | Issue Writer Certificate

Keywords

ALUMINIUM CHLORIDEQ4

PLACENTAL TOXICITYQ4

UTERINE TOXICITYQ4

TERATOGENQ3

Abstract

Background and OBJECTIVE: Aluminum has been known to cause toxic effects on organ systems. Although the knowledge on aluminum (AL) toxicity has markedly improved in recent years, information concerning the reproductive toxicity of this element is still very limited. The purpose of this study was to assess the effect of graded dose of aluminum chloride administered to pregnant mice on their placenta and uterine in a short time. Methods: This study was performed on plug-positive female NMRI (National Medical Research Institute) mice that were randomly divided into six groups (12 mice in each group). Three groups of plug- positive female NMRI mice were given IP injections of ALCL3 at 150 mg/kg on days 10, 11 and 12 of gestation, respectively. Three other groups were given normal saline on the same days as control groups. Mice were killed on day 15 of gestation, the weight and diameter of placenta were recorded. Both placenta and uterus were examined with stereomicroscope and also uterus fixed and stained for microscopic examination.FINDINGS: In all experimental groups, in 14.3%, 13.8% and 13.3% of fetuses, placenta showed abnormal appearance and some degrees of atrophy on days 10, 11, 12 of gestation, respectively that in comparison to control group it was significantly higher (p<0.05). Also, the diameter of placenta in experimental groups (7.2, 7.2 and 7.3mm respectively) was significantly smaller than control groups (7.6mm)(p<0.05). The uterine of AL treated groups showed hemorrhagic area in external examination and infiltration reaction and dispersed necrotic foci in myometer in microscopic examination.Conclusion: According to the results, ALCL3 showed toxic effect on placenta and uterus of pregnant mice. It could explain at least part of TERATOGENic effects of ALCL3

Cites

No record.

References

No record.

Cite

APA: Copy

KARIMPOUR, A., TORABI ZADEH, J., SADUGHI, M., & SADEGHI DARABI, S.S.. (2005). TOXICITY EFFECTS OF ALUMINIUM CHLORIDE ON UTERUS AND PLACENTA OF PREGNANT MICE. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 7(1 (25)), 22-27. SID. https://sid.ir/paper/73500/en

Vancouver: Copy

KARIMPOUR A., TORABI ZADEH J., SADUGHI M., SADEGHI DARABI S.S.. TOXICITY EFFECTS OF ALUMINIUM CHLORIDE ON UTERUS AND PLACENTA OF PREGNANT MICE. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2005;7(1 (25)):22-27. Available from: https://sid.ir/paper/73500/en

IEEE: Copy

A. KARIMPOUR, J. TORABI ZADEH, M. SADUGHI, and S.S. SADEGHI DARABI, “TOXICITY EFFECTS OF ALUMINIUM CHLORIDE ON UTERUS AND PLACENTA OF PREGNANT MICE,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 7, no. 1 (25), pp. 22–27, 2005, [Online]. Available: https://sid.ir/paper/73500/en

Related Journal Papers