The Contingent Prenatal Screening Test for Down’ s Syndrome and Neural Tube Defects in West of Iran (Short Communication)

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AGHAZ FARANAK; Ojagh Seyyedeh Zeinab; Khanjari Saber; VAISI RAYGANI ASAD; KHAZAEI MOZAFAR; BAKHTIARI MITRA

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Journal Paper

Paper Information

Journal: Journal of Reproduction & Infertility Year:2019 | Volume:20 | Issue:4 Page(s): 244-251

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Title

The Contingent Prenatal Screening Test for Down’ s Syndrome and Neural Tube Defects in West of Iran (Short Communication)

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Keywords

Contingent prenatal screening test

Down syndrome

Iran

Neural tube defects

Abstract

Background: The purpose of the study was to evaluate the use of contingent prenatal screening for the detection of Down’ s syndrome and Neural tube defects (NTDs) in west of Iran. Methods: A prospective study was conducted on 653 pregnant women referred to a medical diagnostic laboratory (Imam Reza Clinic, Kermanshah, Iran) for Contingent prenatal screening tests between October 2016 to September 2017. Results: Among 651 women screened in the first trimester, 8 (1. 22%) pregnancies were screen-positive for Down’ s syndrome. In the second trimester, among 605 women, 25 (4. 13%) had a positive result and all of these women voluntarily underwent amniocentesis. Overall, five pregnancies were complicated with chromosomal abnormalities, including five cases of Down’ s syndrome. Conclusion: In a nutshell, the Contingent prenatal screening tests were found to be useful for estimation of Down’ s syndrome as well as NTDs in both young and older mothers in west of Iran. These tests should be performed for pregnant women before an invasive test for Down’ s syndrome.

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APA: Copy

AGHAZ, FARANAK, Ojagh, Seyyedeh Zeinab, Khanjari, Saber, VAISI RAYGANI, ASAD, KHAZAEI, MOZAFAR, & BAKHTIARI, MITRA. (2019). The Contingent Prenatal Screening Test for Down’ s Syndrome and Neural Tube Defects in West of Iran (Short Communication). JOURNAL OF REPRODUCTION AND INFERTILITY, 20(4), 244-251. SID. https://sid.ir/paper/735239/en

Vancouver: Copy

AGHAZ FARANAK, Ojagh Seyyedeh Zeinab, Khanjari Saber, VAISI RAYGANI ASAD, KHAZAEI MOZAFAR, BAKHTIARI MITRA. The Contingent Prenatal Screening Test for Down’ s Syndrome and Neural Tube Defects in West of Iran (Short Communication). JOURNAL OF REPRODUCTION AND INFERTILITY[Internet]. 2019;20(4):244-251. Available from: https://sid.ir/paper/735239/en

IEEE: Copy

FARANAK AGHAZ, Seyyedeh Zeinab Ojagh, Saber Khanjari, ASAD VAISI RAYGANI, MOZAFAR KHAZAEI, and MITRA BAKHTIARI, “The Contingent Prenatal Screening Test for Down’ s Syndrome and Neural Tube Defects in West of Iran (Short Communication),” JOURNAL OF REPRODUCTION AND INFERTILITY, vol. 20, no. 4, pp. 244–251, 2019, [Online]. Available: https://sid.ir/paper/735239/en

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