EFFECT OF METHANOLIC EXTRACT OF NIGELLA SATIVA ON THE RESTING TONE AND NOREADRENALINE INDUCED CONTRACTION OF THORACIC AORTA SMOOTH MUSCLE IN NORMAL AND DIABETIC RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ROUGHANI M.; VASEEI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS) Year:2007 | Volume:9 | Issue:2 (37) Page(s): 7-10

Download Full-Text

Persian Verion

View:

729

Download:

Cites:

Information Journal Paper

Title

EFFECT OF METHANOLIC EXTRACT OF NIGELLA SATIVA ON THE RESTING TONE AND NOREADRENALINE INDUCED CONTRACTION OF THORACIC AORTA SMOOTH MUSCLE IN NORMAL AND DIABETIC RATS

Author(s)

ROUGHANI M. | VASEEI M. | Issue Writer Certificate

Keywords

NIGELLA SATIVAQ3

DIABETES MELLITUSQ3

CONTRACTIONQ2

THORACIC AORTAQ3

RATQ2

Abstract

BACKGROUND AND OBJECTIVE: Considering the significance of medicinal plants with minimum side effects in DIABETES MELLITUS and the relaxant effect of aqueous and alcoholic extract of black seed in isolated tracheal rings, therefore, this study was carried out to evaluate the effect of alcoholic extract of this plant on resting tone and CONTRACTION of THORACIC AORTA from normal and diabetic RATs.METHODS: In this experimental study, adult male RATs (251±14 g) were divided into control and diabetic groups. Streptozotocin (STZ; i.p.) was used for diabetes induction. After 6 weeks, CONTRACTION of isolated rings from endothelium-intact THORACIC AORTA under resting condition and to noreadrenaline in the presence of 100 mg/ml of methanolic extract of NIGELLA SATIVA was recorded.FINDINGS: Although extract pretreatment did not have any significant effect on resting tone of aortic rings from control and diabetic RATs, but the maximum CONTRACTION to noradrenalin was significantly lower in the presence of NIGELLA SATIVA in control RATs (p<0.05). Meanwhile, extract addition did not cause any significant change in diabetic group. CONCLUSION: Methanolic extract of NIGELLA SATIVA is only capable of reducing noradrenalin-induced CONTRACTION in control group and no such effect was observed for diabetic group.

Cites

No record.

References

No record.

Cite

APA: Copy

ROUGHANI, M., & VASEEI, M.. (2007). EFFECT OF METHANOLIC EXTRACT OF NIGELLA SATIVA ON THE RESTING TONE AND NOREADRENALINE INDUCED CONTRACTION OF THORACIC AORTA SMOOTH MUSCLE IN NORMAL AND DIABETIC RATS. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), 9(2 (37)), 7-10. SID. https://sid.ir/paper/73573/en

Vancouver: Copy

ROUGHANI M., VASEEI M.. EFFECT OF METHANOLIC EXTRACT OF NIGELLA SATIVA ON THE RESTING TONE AND NOREADRENALINE INDUCED CONTRACTION OF THORACIC AORTA SMOOTH MUSCLE IN NORMAL AND DIABETIC RATS. JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS)[Internet]. 2007;9(2 (37)):7-10. Available from: https://sid.ir/paper/73573/en

IEEE: Copy

M. ROUGHANI, and M. VASEEI, “EFFECT OF METHANOLIC EXTRACT OF NIGELLA SATIVA ON THE RESTING TONE AND NOREADRENALINE INDUCED CONTRACTION OF THORACIC AORTA SMOOTH MUSCLE IN NORMAL AND DIABETIC RATS,” JOURNAL OF BABOL UNIVERSITY OF MEDICAL SCIENCES (JBUMS), vol. 9, no. 2 (37), pp. 7–10, 2007, [Online]. Available: https://sid.ir/paper/73573/en

Related Journal Papers