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Information Journal Paper

Title

Risk Factors Associated with Heart Valve Thrombosis in Patients with Prosthetic Heart Valve Dysfunction

Pages

  600-604

Abstract

 Background: Thrombotic and thromboembolic events are important causes of mortality and morbidity in patients with prosthetic heart valve. The aim of this study is to evaluate the factors that may contribute to prosthetic heart valve Thrombosis. Methods: This was a cross-sectional study in Rajaie Heart Center on patients with prosthetic heart valve malfunction, within a year. According to the echocardiographic and fluoroscopic findings, the patients were divided into two groups (Thrombosis and non-Thrombosis groups). The patients’ demographic, clinical and laboratory data were recorded and analyzed with SPSS software. Results: A total of 142 patients participated in this study. Ninety-four patients (66. 2%) were diagnosed with Thrombosis. There was a significant relationship between Thrombosis and inadequate anti-coagulation (international normalized rati [INR] <2. 5) (odds ratio [OR]: 4. 15, 95% CI: 1. 98-9. 87, P = 0. 003), history of infection (OR: 12. 81, 95% CI: 3. 52-19. 02, P < 0. 001), prothrombin time (PT) check interval (OR: 2. 38, 95% CI: 1. 63-8. 47, P = 0. 019), atrial fibrillation (AF) rhythm (OR: 3. 96, 95% CI: 1. 75-8. 09, P = 0. 019), and plasma fibrinogen level (OR: 6. 90, 95% CI: 2. 58-14. 69). Conclusion: Based on this study, inadequate anti-coagulation, AF rhythm, recent infection and plasma fibrinogen level were the factors most contributing to prosthetic valve Thrombosis. As there were many cases of Thrombosis in patients with history of infection, this factor can be considered for risk assessment in prosthetic valve.

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    APA: Copy

    Noohi Bezanjani, Feridoun, Gohari, Sepehr, BASSIRI, HOSSEIN ALI, Ahangar, Hassan, & Reshadmanesh, Tara. (2020). Risk Factors Associated with Heart Valve Thrombosis in Patients with Prosthetic Heart Valve Dysfunction. ARCHIVES OF IRANIAN MEDICINE, 23(9), 600-604. SID. https://sid.ir/paper/743294/en

    Vancouver: Copy

    Noohi Bezanjani Feridoun, Gohari Sepehr, BASSIRI HOSSEIN ALI, Ahangar Hassan, Reshadmanesh Tara. Risk Factors Associated with Heart Valve Thrombosis in Patients with Prosthetic Heart Valve Dysfunction. ARCHIVES OF IRANIAN MEDICINE[Internet]. 2020;23(9):600-604. Available from: https://sid.ir/paper/743294/en

    IEEE: Copy

    Feridoun Noohi Bezanjani, Sepehr Gohari, HOSSEIN ALI BASSIRI, Hassan Ahangar, and Tara Reshadmanesh, “Risk Factors Associated with Heart Valve Thrombosis in Patients with Prosthetic Heart Valve Dysfunction,” ARCHIVES OF IRANIAN MEDICINE, vol. 23, no. 9, pp. 600–604, 2020, [Online]. Available: https://sid.ir/paper/743294/en

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