Death from Hemophagocytic Lymphohistiocytosis Syndrome Due to Generalized Hemorrhage

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Kaveh vahid; Keshtkar Rajabi Shahin

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Journal Paper

Paper Information

Journal: Journal of Advances in Medical and Biomedical Research Year:2020 | Volume:28 | Issue:127 Page(s): 119-123

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Information Journal Paper

Title

Death from Hemophagocytic Lymphohistiocytosis Syndrome Due to Generalized Hemorrhage

Author(s)

Kaveh vahid | Keshtkar Rajabi Shahin | Issue Writer Certificate

Keywords

Diagnosis

Epidemiology

Hemophagocytic lymphohistiocytosis

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is the result of excessive cytokine release, leading to over-response by immune cells, such as macrophages and T lymphocytes. Here, we report a lethal case of HLH with a complete clinical course. The patient was a 45-year-old man with fever and chills since two months ago plus splenomegaly, hepatomegaly, and pancytopenia. The Anti-HBc IgM was positive, but the HBS antigen, anti-HCV, and HBS antibody were negative. Assessment for cirrhosis was carried out by FibroScan, which showed F4 grade. The biopsy sampling was impossible due to the low platelet count. During admission, generalized bleeding was developed and led to alveolar hemorrhage, which subsequently resulted in the patient's death. Liver necropsy certified the Diagnosis of hemophagocytic syndrome. Overall, according to the reported case in this paper, it should be remembered that secondary HLH is an inflammatory phenomenon due to different conditions, such as latent newly-developed infections.

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APA: Copy

Kaveh, vahid, & Keshtkar Rajabi, Shahin. (2020). Death from Hemophagocytic Lymphohistiocytosis Syndrome Due to Generalized Hemorrhage. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, 28(127), 119-123. SID. https://sid.ir/paper/744957/en

Vancouver: Copy

Kaveh vahid, Keshtkar Rajabi Shahin. Death from Hemophagocytic Lymphohistiocytosis Syndrome Due to Generalized Hemorrhage. JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH[Internet]. 2020;28(127):119-123. Available from: https://sid.ir/paper/744957/en

IEEE: Copy

vahid Kaveh, and Shahin Keshtkar Rajabi, “Death from Hemophagocytic Lymphohistiocytosis Syndrome Due to Generalized Hemorrhage,” JOURNAL OF ADVANCES IN MEDICAL AND BIOMEDICAL RESEARCH, vol. 28, no. 127, pp. 119–123, 2020, [Online]. Available: https://sid.ir/paper/744957/en

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