EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, GASP-1, IGF-I AND IGFBP-3 IN YOUNG MEN

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GHARAKHANLOU R.; SAREMI A.; OMIDFAR K.; SHARGHI S.; GHERAATI M.R.

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Title

EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, GASP-1, IGF-I AND IGFBP-3 IN YOUNG MEN

Author(s)

Keywords

MYOSTATINQ2

IGF-IQ3

GASP-1Q2

RESISTANCE TRAININGQ2

Abstract

The purpose of this study was to determine the effect of eight weeks RESISTANCE TRAINING on muscle strength, lean body mass, serum MYOSTATIN, GASP-1, IGF-I and IGFBP-3 in untrained young men. Sixteen young men (19-26 years) were assigned to RESISTANCE TRAINING (n=8) or control (n=8) groups. The training protocol consisted of thrice weekly using three sets of eight to ten repetitions at 60-70% of 1RM for whole-body exercises, whereas control group performed no RESISTANCE TRAINING. Blood sampling, muscular strength test and body composition analysis (DEXA), were performed at 0, 4th and 8th weeks. MYOSTATIN, GASP-1, and IGFBP-3 measured by enzyme immuno assay, wherease IGF-I was determined via immunoradiometric. Result showed that RESISTANCE TRAINING caused significant increases in muscular strength [between weeks 0 and 4 (P<0.05), and weeks 4 and 8 (P<0.05)], lean body mass [between weeks 0 and 8 (P<0.05)] and GASP-1 [between weeks 0 and 8 (P<0.05)], whereas MYOSTATIN were decreased [between weeks 0 and 4 (P<0.05), and weeks 4 and 8 (P<0.05)]. But significant change in serum levels of IGF-I and IGFBP-3 did not observe. The findings of this study suggest that 8 weeks RESISTANCE TRAINING does not alter serum levels of IGF-I and IGFBP-3, and decreasing MYOSTATIN production and inhabitation of its function by GASP-1 may play important role in increasing muscle strength and muscle mass which induced by RESISTANCE TRAINING.

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APA: Copy

GHARAKHANLOU, R., SAREMI, A., OMIDFAR, K., SHARGHI, S., & GHERAATI, M.R.. (2009). EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, GASP-1, IGF-I AND IGFBP-3 IN YOUNG MEN. JOURNAL OF MOVEMENT SCIENCE & SPORTS, 7(13), 67-79. SID. https://sid.ir/paper/74793/en

Vancouver: Copy

GHARAKHANLOU R., SAREMI A., OMIDFAR K., SHARGHI S., GHERAATI M.R.. EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, GASP-1, IGF-I AND IGFBP-3 IN YOUNG MEN. JOURNAL OF MOVEMENT SCIENCE & SPORTS[Internet]. 2009;7(13):67-79. Available from: https://sid.ir/paper/74793/en

IEEE: Copy

R. GHARAKHANLOU, A. SAREMI, K. OMIDFAR, S. SHARGHI, and M.R. GHERAATI, “EFFECT OF RESISTANCE TRAINING ON SERUM MYOSTATIN, GASP-1, IGF-I AND IGFBP-3 IN YOUNG MEN,” JOURNAL OF MOVEMENT SCIENCE & SPORTS, vol. 7, no. 13, pp. 67–79, 2009, [Online]. Available: https://sid.ir/paper/74793/en

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