EFFECT OF WEIGHT-TRAINING AND CREATINE LOADING ON THE CELLULAR DAMAGE INDICES ENZYMES ACTIVITY IN NON-ATHLETIC MALE STUDENTS

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BASHIRI JABAR; GAINI ABASS ALI; NIKBAKHT HOJATOLLAH; HADI HAMDOLAH; BASHIRI MEHDI

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Journal: JOURNAL OF MOVEMENT SCIENCE & SPORTS Year:2010 | Volume:7 | Issue:14 Page(s): 61-68

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Title

EFFECT OF WEIGHT-TRAINING AND CREATINE LOADING ON THE CELLULAR DAMAGE INDICES ENZYMES ACTIVITY IN NON-ATHLETIC MALE STUDENTS

Author(s)

Keywords

MYOSTATINQ3

IGF-IQ3

GASP-1Q3

RESISTANCE TRAININGQ3

Abstract

The purpose of this study was to determine the effect of eight weeks RESISTANCE TRAINING on muscle strength, lean body mass, serum MYOSTATIN, GASP-1, IGF-I and IGFBP-3 in untrained young men. Sixteen young men (19-26 years) were assigned to RESISTANCE TRAINING (n=8) or control (n=8) groups. The training protocol consisted of thrice weekly using three sets of eight to ten repetitions at 60-70% of 1RM for whole-body exercises, whereas control group performed no RESISTANCE TRAINING. Blood sampling, muscular strength test and body composition analysis (DEXA), were performed at 0, 4th and 8th weeks. MYOSTATIN, GASP-1, and IGFBP-3 measured by enzyme immuno assay, wherease IGF-I was determined via immunoradiometric. Result showed that RESISTANCE TRAINING caused significant increases in muscular strength [between weeks 0 and 4 (P<0.05), and weeks 4 and 8 (P<0.05)], lean body mass [between weeks 0 and 8 (P<0.05)] and GASP-1 [between weeks 0 and 8 (P<0.05)], whereas MYOSTATIN were decreased [between weeks 0 and 4 (P<0.05), and weeks 4 and 8 (P<0.05)]. But significant change in serum levels of IGF-I and IGFBP-3 did not observe. The findings of this study suggest that 8 weeks RESISTANCE TRAINING does not alter serum levels of IGF-I and IGFBP-3, and decreasing MYOSTATIN production and inhibitation of its function by GASP-1 may play important role in increasing muscle strength and muscle mass which induced by RESISTANCE TRAINING.

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References

THE INTERACTION EFFECTS OF VITAMIN E SUPPLEMENTATION AND AEROBIC TRAINING ON CK, LDH AND BLOOD LACTATE OF UNTRAINED MEN AFTER EXHAUSTIVE EXERCISE

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APA: Copy

BASHIRI, JABAR, GAINI, ABASS ALI, NIKBAKHT, HOJATOLLAH, HADI, HAMDOLAH, & BASHIRI, MEHDI. (2010). EFFECT OF WEIGHT-TRAINING AND CREATINE LOADING ON THE CELLULAR DAMAGE INDICES ENZYMES ACTIVITY IN NON-ATHLETIC MALE STUDENTS. JOURNAL OF MOVEMENT SCIENCE & SPORTS, 7(14), 61-68. SID. https://sid.ir/paper/74872/en

Vancouver: Copy

BASHIRI JABAR, GAINI ABASS ALI, NIKBAKHT HOJATOLLAH, HADI HAMDOLAH, BASHIRI MEHDI. EFFECT OF WEIGHT-TRAINING AND CREATINE LOADING ON THE CELLULAR DAMAGE INDICES ENZYMES ACTIVITY IN NON-ATHLETIC MALE STUDENTS. JOURNAL OF MOVEMENT SCIENCE & SPORTS[Internet]. 2010;7(14):61-68. Available from: https://sid.ir/paper/74872/en

IEEE: Copy

JABAR BASHIRI, ABASS ALI GAINI, HOJATOLLAH NIKBAKHT, HAMDOLAH HADI, and MEHDI BASHIRI, “EFFECT OF WEIGHT-TRAINING AND CREATINE LOADING ON THE CELLULAR DAMAGE INDICES ENZYMES ACTIVITY IN NON-ATHLETIC MALE STUDENTS,” JOURNAL OF MOVEMENT SCIENCE & SPORTS, vol. 7, no. 14, pp. 61–68, 2010, [Online]. Available: https://sid.ir/paper/74872/en

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