Portal Vein Thrombosis and Budd-Chiari Syndrome as the Initial Symptom of Polycythemia Vera and Hyperhomocysteinemia

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Pazooki Behshad; Radkhah Hanieh; Sherafati Alborz

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Title

Portal Vein Thrombosis and Budd-Chiari Syndrome as the Initial Symptom of Polycythemia Vera and Hyperhomocysteinemia

Author(s)

Pazooki Behshad | Radkhah Hanieh | Sherafati Alborz | Issue Writer Certificate

Keywords

Portal vein thrombosis

Polycythemia vera

Budd-Chiari syndrome

Hyperhomocysteinemia

Abstract

Portal vein thrombosis (PVT), commonly associated with cirrhosis of liver and thrombophilia, is one of the causes of severe abdominal pain. In the absence of non-cirrhotic non-malignant extrahepatic Portal vein thrombosis, Myeloproliferative Disease (MPD) and an underlying thrombotic disorder should always be suspected and investigated. Hyperhomocysteinemia has been well-documented to increase the risk of arterial thrombotic events, peripheral arterial disease, and stroke. It is also a risk factor for deep-vein thrombosis. In the general population, association with Portal vein thrombosis is very unusual, and only a few cases have been reported. We describe a case of Polycythemia vera (PV) and Hyperhomocysteinemia presenting with severe abdominal pain due to Portal vein thrombosis. The patient underwent phlebotomy and was prescribed life-long anticoagulant, aspirin, vitamin B6, vitamin B12, and folic acid, then referred to a hematologist.

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APA: Copy

Pazooki, Behshad, Radkhah, Hanieh, & Sherafati, Alborz. (2019). Portal Vein Thrombosis and Budd-Chiari Syndrome as the Initial Symptom of Polycythemia Vera and Hyperhomocysteinemia. CASE REPORTS IN CLINICAL PRACTICE, 4(2), 40-43. SID. https://sid.ir/paper/750563/en

Vancouver: Copy

Pazooki Behshad, Radkhah Hanieh, Sherafati Alborz. Portal Vein Thrombosis and Budd-Chiari Syndrome as the Initial Symptom of Polycythemia Vera and Hyperhomocysteinemia. CASE REPORTS IN CLINICAL PRACTICE[Internet]. 2019;4(2):40-43. Available from: https://sid.ir/paper/750563/en

IEEE: Copy

Behshad Pazooki, Hanieh Radkhah, and Alborz Sherafati, “Portal Vein Thrombosis and Budd-Chiari Syndrome as the Initial Symptom of Polycythemia Vera and Hyperhomocysteinemia,” CASE REPORTS IN CLINICAL PRACTICE, vol. 4, no. 2, pp. 40–43, 2019, [Online]. Available: https://sid.ir/paper/750563/en

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