THE EFFECT OF AMYGDALA LESION ON ANTERIOR CLAUSTRUM KINDLED SEIZURES IN RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAFARI F.; SABET KASAEI M.; SADEGHI YOUSEF; MOHAMMADZADEH MOHAMMAD; DELJOU F.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Physiology and Pharmacology Year:2008 | Volume:11 | Issue:4 Page(s): 312-319

Download Full-Text

Persian Verion

View:

1,058

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF AMYGDALA LESION ON ANTERIOR CLAUSTRUM KINDLED SEIZURES IN RATS

Author(s)

Keywords

ANTERIOR CLAUSTRUMQ3

KINDLINGQ3

AMYGDALA LESIONQ3

Abstract

Introduction: The claustrum interconnects with different regions and also projects to the hippocampus and the amygdala. The role of claustrum in the complex partial seizure is not clear. In the current study, the effect of amygdale lesion on ANTERIOR CLAUSTRUM kindled seizures in rat was investigated.Methods: Male Wistar rats, weighting 250-300 g, were received DC current via a bipolar electrode inserted in right basolateral amygdala. A tripolar electrode for stimulation and electroencephalography recording in the right ANTERIOR CLAUSTRUM has been fixed. After a 10 days period of recovery, animals were daily received KINDLING stimulation (60 Hz, for 2s, with 1 ms pulse duration) and KINDLING parameters were measured. Control animals did not receive the DC current. Two lesion groups respectively received DC current before KINDLING stimulations and after full kindled statement achievement.Results: Our results showed that AMYGDALA LESION, was capable of delaying claustrum KINDLING with increasing the stimulation trials required to kindle to seizure stages. Furthermore the lesion reduced the severity of established kindled seizures by decreasing the stage 5 duration and after discharge durations.Conclusion: AMYGDALA LESION had no effect on the expression of generalized seizures and claustrum play an important role in the propagation of epileptic seizure. Whereas the amygdala has a facilitators role in propagation claustrum kindled seizure.

Cites

No record.

References

No record.

Cite

APA: Copy

ZAFARI, F., SABET KASAEI, M., SADEGHI, YOUSEF, MOHAMMADZADEH, MOHAMMAD, & DELJOU, F.. (2008). THE EFFECT OF AMYGDALA LESION ON ANTERIOR CLAUSTRUM KINDLED SEIZURES IN RATS. PHYSIOLOGY AND PHARMACOLOGY, 11(4), 312-319. SID. https://sid.ir/paper/75151/en

Vancouver: Copy

ZAFARI F., SABET KASAEI M., SADEGHI YOUSEF, MOHAMMADZADEH MOHAMMAD, DELJOU F.. THE EFFECT OF AMYGDALA LESION ON ANTERIOR CLAUSTRUM KINDLED SEIZURES IN RATS. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2008;11(4):312-319. Available from: https://sid.ir/paper/75151/en

IEEE: Copy

F. ZAFARI, M. SABET KASAEI, YOUSEF SADEGHI, MOHAMMAD MOHAMMADZADEH, and F. DELJOU, “THE EFFECT OF AMYGDALA LESION ON ANTERIOR CLAUSTRUM KINDLED SEIZURES IN RATS,” PHYSIOLOGY AND PHARMACOLOGY, vol. 11, no. 4, pp. 312–319, 2008, [Online]. Available: https://sid.ir/paper/75151/en

Related Journal Papers