THE EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE) ON REDUCTION OF PAIN IN PATIENTS WITH OSTEOARTHRITIS: A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL

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HAGHIGHI M.; KHALVAT A.; TOULIAT T.; FALAH HOSSEINI H.; JALAEI SHOHREH; ESHRAGHIAN M.R.; EBRAHIMI VARKIANI A.

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Journal: Physiology and Pharmacology Year:2003 | Volume:7 | Issue:1 Page(s): 65-72

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Title

THE EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE) ON REDUCTION OF PAIN IN PATIENTS WITH OSTEOARTHRITIS: A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL

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Keywords

GINGERQ2

ETHANOLIC EXTRACTQ3

OSTEOARTHRITISQ3

PAINQ2

ALTERNATIVE MEDICINEQ4

Abstract

Patients with chronic, PAINful diseases often seek alternative therapy. GINGER is one of the most popular herbal medications for rheumatic diseases. However, there are few experimental documents on its beneficial effects. Therefore, in this study the effect of ethanolic GINGER extract and placebo were examined on 80 patients with OSTEOARTHRITIS. The patients were randomized into two treatment groups (control and GINGER extract, n=40) and taken either two capsules containing 30 mg GINGER extract or placebo daily for a period of one month. Acetaminophen was used as rescue medication throughout the study. The results showed that GINGER extract was more effective than placebo in reducing mechanical and gelling PAIN in patients with OSTEOARTHRITIS. Furthermore, there were not any side effects during the treatment period with these medications. Taken together, it is concluded that instead of non-steroidal anti-inflammatory drugs, GINGER extract might be used as a suitable ALTERNATIVE MEDICINE and/or supplementation in reducing the PAIN in patients with OSTEOARTHRITIS.

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APA: Copy

HAGHIGHI, M., KHALVAT, A., TOULIAT, T., FALAH HOSSEINI, H., JALAEI, SHOHREH, ESHRAGHIAN, M.R., & EBRAHIMI VARKIANI, A.. (2003). THE EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE) ON REDUCTION OF PAIN IN PATIENTS WITH OSTEOARTHRITIS: A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL. PHYSIOLOGY AND PHARMACOLOGY, 7(1), 65-72. SID. https://sid.ir/paper/75165/en

Vancouver: Copy

HAGHIGHI M., KHALVAT A., TOULIAT T., FALAH HOSSEINI H., JALAEI SHOHREH, ESHRAGHIAN M.R., EBRAHIMI VARKIANI A.. THE EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE) ON REDUCTION OF PAIN IN PATIENTS WITH OSTEOARTHRITIS: A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL. PHYSIOLOGY AND PHARMACOLOGY[Internet]. 2003;7(1):65-72. Available from: https://sid.ir/paper/75165/en

IEEE: Copy

M. HAGHIGHI, A. KHALVAT, T. TOULIAT, H. FALAH HOSSEINI, SHOHREH JALAEI, M.R. ESHRAGHIAN, and A. EBRAHIMI VARKIANI, “THE EFFECT OF GINGER EXTRACT (ZINGIBER OFFICINALE) ON REDUCTION OF PAIN IN PATIENTS WITH OSTEOARTHRITIS: A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED TRIAL,” PHYSIOLOGY AND PHARMACOLOGY, vol. 7, no. 1, pp. 65–72, 2003, [Online]. Available: https://sid.ir/paper/75165/en

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