EFFECT OF GINGER (ZINGIBER OFFICINALE) HYDROETHANOLIC EXTRACT ON ANALGESIA INDUCED BY MORPHINE IN ADULT MALE RATS

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GOMAR A.; MIRAZI N.; GOMAR M.

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Journal: Journal of Ilam University of Medical Sciences Year:2014 | Volume:22 | Issue:SUPPLEMENT Page(s): 74-82

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Title

EFFECT OF GINGER (ZINGIBER OFFICINALE) HYDROETHANOLIC EXTRACT ON ANALGESIA INDUCED BY MORPHINE IN ADULT MALE RATS

Author(s)

GOMAR A. | MIRAZI N. | GOMAR M. | Issue Writer Certificate

Keywords

GINGER HYDROETHANOLIC EXTRACTQ1

PAINQ2

MORPHINEQ2

Abstract

Introduction: In addition to chemical drugs, the role of herbal remedies such as ginger should also be noted in fighting against PAIN. MORPHINE is a common PAIN medication. This study investigated the effect of ginger rhizome Hydroethanolic extract on analgesia induced by MORPHINE in adult male rats.Materials & Methods: In this study, male Wistar rats in the weight range of 150±15 g were used. The mice were randomly divided into six groups of six. 30 min after prescription, the rats Tail-flick test was performed and the results were analyzed as mean- ±SEM and by ANOVA (One way ANOVA) and Tukey test. Data differences with P<0.05 was considered significant. Findings: Results showed that the ginger extract relieved PAIN in tail-flick test in all receiving groups (P 0.001). The extract could increase the anti-pain effects of MORPHINE (P 0.05).Discussion & Conclusion: Our observations indicated that Ginger may interfere with the central system involved in PAIN pathways which can reduce PAIN in rats. In the way, Ginger extract can increase the analgesic effect of MORPHINE. Also, due to the side effects of MORPHINE, it can be combined with Ginger juice and to be used for relieving PAIN. By doing so, the reduction in MORPHINE consumption will have fewer side effects.

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APA: Copy

GOMAR, A., MIRAZI, N., & GOMAR, M.. (2014). EFFECT OF GINGER (ZINGIBER OFFICINALE) HYDROETHANOLIC EXTRACT ON ANALGESIA INDUCED BY MORPHINE IN ADULT MALE RATS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, 22(SUPPLEMENT), 74-82. SID. https://sid.ir/paper/90245/en

Vancouver: Copy

GOMAR A., MIRAZI N., GOMAR M.. EFFECT OF GINGER (ZINGIBER OFFICINALE) HYDROETHANOLIC EXTRACT ON ANALGESIA INDUCED BY MORPHINE IN ADULT MALE RATS. JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;22(SUPPLEMENT):74-82. Available from: https://sid.ir/paper/90245/en

IEEE: Copy

A. GOMAR, N. MIRAZI, and M. GOMAR, “EFFECT OF GINGER (ZINGIBER OFFICINALE) HYDROETHANOLIC EXTRACT ON ANALGESIA INDUCED BY MORPHINE IN ADULT MALE RATS,” JOURNAL OF ILAM UNIVERSITY OF MEDICAL SCIENCES, vol. 22, no. SUPPLEMENT, pp. 74–82, 2014, [Online]. Available: https://sid.ir/paper/90245/en

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